Publications by authors named "Z I Balogh"
Cell-free mitochondria are detected in high concentrations in the plasma of orthopedic trauma patients.
J Trauma Acute Care Surg
December 2024
Article Synopsis
- Trauma patients have significantly higher levels of cell-free mitochondria in their blood compared to healthy individuals, especially right after surgery, which declines by day 5 post-op.
- These active cell-free mitochondria correlate with tissue injury severity, indicating a relationship with complications like acute thrombocytopenia and organ failure.
- While high levels of cell-free mitochondria aren't directly inflammatory, their active form may contribute to more severe secondary tissue injuries in trauma patients.
Aims: Surgeon and patient reluctance to participate are potential significant barriers to conducting placebo-controlled trials of orthopaedic surgery. Understanding the preferences of orthopaedic surgeons and patients regarding the design of randomized placebo-controlled trials (RCT-Ps) of knee procedures can help to identify what RCT-P features will lead to the greatest participation. This information could inform future trial designs and feasibility assessments.
View Article and Find Full Text PDFArticle Synopsis
- The management of blunt splenic trauma differs between children and adults, influenced by guidelines from organizations like the APSA and WTA, particularly regarding treatment methods like splenectomy and angioembolization.* -
- A comparison of the 2023 guidelines revealed that while initial resuscitation is standard, the management strategies diverge: adults' care is guided by both CT findings and hemodynamic status, while children's care relies solely on hemodynamics.* -
- Differences in ICU admission, follow-up protocols, and thromoprophylaxis use highlight the distinct approaches for each age group, suggesting a need for unified guidelines that cater to the specific needs of both children and adults.*