[Modulating effect of estradiol on the sensitivity of the preoptic area neurons to noradrenaline].

Sensitivity of the preoptic area neurons to norepinephrine before and after application of estradiol was investigated. The obtained results show that estradiol influences neuron sensitivity. Microiontophoretic application of norepinephrine followed the estradiol into the preoptic area and increased the activity of single neurons in the majority of experiments.

[Estrogen-sensitive neurons of the preoptic area of the hypothalamus].

Microiontophoretic application of estradiol to the preoptic area of the hypothalamus enhanced the unit activity, the response being more obvious at the diestrus-2 stage and owing to the level of endogenous estrogens.