Publications by authors named "Z Hina Zarei"

Background: COVID-19 is a pandemic involving coinfection with other opportunistic microorganisms, including parasites such as Leishmania infantum. The present study aimed to determine the frequency of L. infantum infection and its role in disease and mortality among symptomatic COVID-19 patients in comparison with the non-COVID-19 control group in the endemic area of visceral leishmaniasis (VL) in Iran.

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  • An oral irrigator, or dental waterjet (DWJ), is used to remove plaque and improve oral hygiene, particularly in orthodontic patients.
  • A systematic review and meta-analysis of seven clinical trials evaluated the effectiveness of DWJ against traditional brushing methods, revealing no significant differences in gum health or plaque removal between DWJ and other tools like automatic or manual toothbrushes.
  • The overall evidence quality was low to very low, suggesting that while DWJ might be a useful tool, it does not significantly outperform traditional oral hygiene methods for orthodontic patients.
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  • * The researchers tested the new Cs/PF/MTF formulation's effectiveness against both the parasite stages in vitro and in vivo on naturally infected dogs, finding it significantly more potent than standard miltefosine.
  • * The new formulation was well-tolerated in dogs, with successful intravenous doses of 170 μg/kg administered daily for 28 days, indicating potential for improved treatment outcomes in CVL.
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Self-assembled peptide nanoparticles are unique stimuli responsive biodegradable materials with applications in biomedicines as delivery carriers and imaging agents. This study investigates the controlled self-assembly of chicken Angiogenin 4 derived immunomodulatory macrocyclic peptide (mCA4-5) in the presence of an inert amphipathic stabilizing peptide and as a function of pH, temperature and presence of ions to yield optically active, physiologically stable and biodegradable peptide nanoparticles. The photoluminescent peptide nanoparticles (PLPNs) produced were characterized for the size, surface charge, optical properties and crystallinity.

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  • Oral conditions like recurrent aphthous stomatitis can greatly impact quality of life, prompting research into new treatment methods.
  • This study develops a novel buccal mucoadhesive hydrogel using methacrylate hydroxypropyl methylcellulose and methacrylate lignin, combined with nanostructured lipid carriers to control the release of a compound called alpha-pinene.
  • The resulting nanocomposite hydrogel showed improved mechanical strength, reduced energy loss during compression, controlled release of alpha-pinene over 96 hours, and enhanced adhesive properties, indicating potential for effective treatment in oral health applications.
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