Publications by authors named "Z Hidayati"
Article Synopsis
- In Indonesia, early-onset colorectal cancer (EOCRC) occurs more frequently in those under 50, potentially linked to a higher incidence of Lynch syndrome (LS) among CRC patients.
- A study at Dr. Sardjito General Hospital examined 244 samples for mutations in KRAS and PIK3CA, finding significant associations between these mutations, microsatellite instability (MSI) status, and Lynch syndrome.
- Results indicated that KRAS mutations correlate with right-sided colorectal cancer and higher histology grades, while PIK3CA mutations link to female patients and lower tumor-infiltrating lymphocyte levels; however, neither mutation significantly impacted overall survival.
Introduction: Breast-conserving surgery (BCS) with radiation therapy is the procedure of choice for early-stage breast cancer. Survival and locoregional recurrence is non-inferior to mastectomy, with superior cosmetic and psycho-social outcomes. Differing health systems have demonstrated a wide variation in the rate of BCS.
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