Publications by authors named "Z Hamady"

Background: Aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) usage has been associated with pancreatic ductal adenocarcinoma (PDAC) prevention, though epidemiological data have not reliably demonstrated this. The aim of this study is to identify if aspirin and other NSAIDs are effective in the primary prevention of PDAC in a large UK prospective cohort.

Methods: A nested case-control study was conducted using the UK Biobank cohort.

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Aims: To evaluate the safety profile of robotic cholecystectomy performed within the United Kingdom (UK) Robotic Hepatopancreatobiliary (HPB) training programme.

Methods: A retrospective evaluation of prospectively collected data from eleven centres participating in the UK Robotic HPB training programme was conducted. All adult patients undergoing robotic cholecystectomy for symptomatic gallstone disease or gallbladder polyp were considered.

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Article Synopsis
  • The study looked at how diabetes affects patients with pancreatic cancer who had surgery to remove part of their pancreas.
  • They found that having diabetes didn't change the chances of surviving for five years or the chances of cancer coming back after surgery.
  • So, doctors can treat diabetic patients the same as those without diabetes when considering surgery.
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Article Synopsis
  • Patients undergoing pancreaticoduodenectomy for distal cholangiocarcinoma (dCCA) have a high recurrence rate, with 65% developing recurrence mostly within three years post-surgery.
  • The study identified common recurrence patterns, including local, distant, and mixed types, with primary sites being the pancreatic bed, liver, and lungs.
  • Key predictive factors for recurrence included cancer stage, type of surgical resection, and various histological features, helping inform potential follow-up treatments or strategies.
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Pancreatic ductal adenocarcinoma (PDAC) is usually diagnosed late, leading to a high mortality rate. Early detection facilitates better treatment options. The aim of this UK-based case-control study was to determine whether two validated tests for pancreatic exocrine insufficiency (PEI), namely, the C-mixed triglyceride breath test (C-MTGBT) and a faecal elastase (FE-1) test, can discriminate between patients with resectable PDAC versus healthy volunteers (HVs) along with a comparison group with chronic pancreatitis (CP).

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