Renal Involvement in Mediterranean Spotted Fever: Clinical and Histopathological Data.

Objective: Mediterranean spotted fever (MSF) is a tick-borne rickettsial infection endemic to the Mediterranean coastline countries. As a result of growing tourism, imported cases have been registered in many nonendemic countries and regions. We present clinical laboratory parameters and histopathological data on renal impairment in patients with MSF.

Bisphosphonate-associated osteonecrosis of the jaws -- report of three cases in Bulgaria and review of the literature.

A severe complication of the administration of bisphosphonate-containing medications is known as bisphosphonate-associated osteonecrosis of the jaws (BONJ). A case series of three patients affected by BONJ is presented. These patients currently represent the only described cases of BONJ in Bulgaria.

[Adenocarcinoma of the pancreas with distant meningeal metastasis].

The incidence of meningeal metastasis from pancreatic cancer is extremely low. In our country patients die rapidly from pancreatic cancer and are extremely rarely subjected to autopsy--they either die at home, or complications from primary tumor result in low clinical interest. We had the rare chance to perform an autopsy on a female patient with meningeal spread of pancreatic carcinoma, in which the patient initially developed signs of neurologic disorder without exhibiting any symptoms of pancreatic disease.