[Mechanism of salicylic acid ameliorates salt-induced changes in Andrographis paniculata].

In this study, Andrographis paniculata seedlings were used as experimental materials to study the effects of salicylic acid(SA) on the growth and effective component accumulation of A. paniculata under NaCl stress. The results showed that with the increase of NaCl concentration, the growth of A.

Determination of azithromycin in human plasma by LC-MS-MS and its pharmacokinetics.

A LC-MS-MS assay has been developed for determinating of azithromycin in human plasma and investigating the pharmacokinetics in Chinese male volunteers following oral administration of a single dose of the capsules (0.5 g). Plasma samples were deproteinated by methanol and a liquid chromatographic-mass-mass spectrometric assay was developed for the determination of azithromycin in human plasma.

Polarization and apoptosis of T cell subsets in idiopathic thrombocytopenic purpura.

It is well known that idiopathic thrombocytopenic purpura (ITP) is an acquired organ-specific autoimmune hemorrhagic disease and dysfunctional cellular immunity is considered important in the pathophysiology of ITP, however, polarization and apoptosis profiles of T lymphocytes remain unclear completely. In this paper, we investigated the polarization of T cell subsets, the expressions of apoptotic proteins Fas/FasL on T cell subsets and the level of antiapoptotic gene bcl-2 and bax mRNA in the bcl-2 family, then discussed the role of them in ITP pathogenesis. We demonstrated that the ratios of Th1/Th2 and Tc1/Tc2 in ITP children increased obviously, the average percentages of Th1 and Th2 also increased clearly, but the average percentages of Tc1 and Tc2 did not changed.