Thermodynamic performance of organic rankine cycle based pumped thermal energy storage system with different working fluids.

In the context of global efforts toward energy transition and carbon neutrality, thermal integrated pumped thermal energy storage (TIPTES) systems, especially those utilizing low-grade heat sources, have garnered significant attention due to their large capacity, flexibility, and environmental advantages. This paper explores a TIPTES system that harnesses industrial waste heat as a heat source. The system's heat pump (HP) subcycle and Organic Rankine Cycle (ORC) subcycle are equipped with regenerators to optimize system configuration and enhance efficiency.

Network pharmacology uncovers that secoisolariciresinol diglucoside ameliorate premature ovarian insufficiency via PI3K/Akt pathway.

As one of the essential lignan derivative found in traditional Chinese medicinal herbs, secoisolariciresinol diglucoside (SDG) was proved to promote women's health through its phytoestrogenic properties. Increasingly studies indicated that this compound could be a potential drug capable of preventing estrogen-related diseases. Here, we aimed to investigate whether SDG can counteract cyclophosphamide (CTX) induced premature ovarian insufficiency (POI) and further explore its specific molecular mechanism.

Glycyrrhizic acid reduces neutrophil extracellular trap formation to ameliorate colitis-associated colorectal cancer by inhibiting peptidyl arginine deiminase 4.

Ethnopharmacological Relevance: In traditional Chinese medicine, the radices of Glycyrrhiza uralensis Fisch, known as liquorice, have been used for relieving cough, alleviating pain and harmonizing the actions of all medicinals in a formula. Glycyrrhizic acid (GA), a natural compound derived from licorice, exhibits notable anti-inflammatory properties.

Aim: Neutrophil extracellular trap (NET) generated by peptidylarginine deiminase 4 (PAD4) has been implicated in the progression of colitis to colitis-associated colorectal cancer (CAC).

Deciphering the driving mechanism of microbial community for rapid stabilization and lignocellulose degradation during waste semi-aerobic bioreactor landfilling with multifunctional microbial inoculum.

Owing to the massive refractory lignocellulose and leachate-organic loads, the stabilization of municipal solid waste (MSW) landfill is often prolonged, resulting in environmental burdens. Herein, various assembled multifunctional microbial inoculums (MMIs) were introduced into the semi-aerobic bioreactor landfill (SABL) to investigate the bioaugmentation impacts. Compared to control (CK) and other MMIs treatments (G1-G3), LD + LT + DM inoculation (G4) significantly increased volatile solids degradation (9.

Advancements in nanohydroxyapatite: synthesis, biomedical applications and composite developments.

Nanohydroxyapatite (nHA) is distinguished by its exceptional biocompatibility, bioactivity and biodegradability, qualities attributed to its similarity to the mineral component of human bone. This review discusses the synthesis techniques of nHA, highlighting how these methods shape its physicochemical attributes and, in turn, its utility in biomedical applications. The versatility of nHA is further enhanced by doping with biologically significant ions like magnesium or zinc, which can improve its bioactivity and confer therapeutic properties.