Precise Measurement of the e^{+}e^{-}→D_{s}^{+}D_{s}^{-} Cross Section at Center-of-Mass Energies from Threshold to 4.95 GeV.

Using the e^{+}e^{-} collision data collected with the BESIII detector operating at the BEPCII collider, at center-of-mass energies from the threshold to 4.95 GeV, we present precise measurements of the cross section for the process e^{+}e^{-}→D_{s}^{+}D_{s}^{-} using a single-tag method. The resulting cross section line shape exhibits several new structures, thereby offering an input for a future coupled-channel analysis and model tests, which are critical to understand vector charmonium-like states with masses between 4 and 5 GeV.

Polarization-independent dual-peak filter based on a cylindrically symmetric helical small-period fiber grating.

A polarization-independent dual-peak narrow-band filter is proposed and demonstrated theoretically and experimentally, which is realized by using a helical long-period fiber grating (HLPG) but with a period small down to tens of micrometers. Unlike those excessively tilted fiber gratings (Ex-TFGs) or the conventional long-period fiber gratings (LPGs) but with a small period down to tens of micrometers where the generated dual-peak pairs (DPPs) are all of the strong polarization-dependence, the DPPs obtained in this study are of the polarization-independent, which is the first time, to the best of our knowledge, that the underlying mechanism for generation of the polarization-independent DPPs in transmission spectrum of the helical small-period fiber grating (HSPFG) has been revealed both theoretically and experimentally.

Real-world safety evaluation of brivaracetam: insights from the US FDA adverse event reporting system.

Background: Brivaracetam (BRV) is a novel drug for the treatment of epilepsy. This study aimed to detect and characterize adverse events (AEs) associated with BRV from the first quarter of 2016 to the second quarter of 2024 using the U.S.

Myokines: metabolic regulation in obesity and type 2 diabetes.

Skeletal muscle plays a vital role in the regulation of systemic metabolism, partly through its secretion of endocrine factors which are collectively known as myokines. Altered myokine levels are associated with metabolic diseases, such as type 2 diabetes (T2D). The significance of interorgan crosstalk, particularly through myokines, has emerged as a fundamental aspect of nutrient and energy homeostasis.

Icariin modulates osteogenic and adipogenic differentiation in ADSCs via the Hippo-YAP/TAZ pathway: a novel therapeutic strategy for osteoporosis.

Background: Adipose-derived stem cell (ADSC) transplantation presents a promising approach for osteoporosis (OP) treatment. However, the therapeutic efficacy of ADSCs is hindered by low post-transplantation survival rates and limited capacities for adhesion, migration, and differentiation. Icariin (ICA), the primary active compound of Epimedium, has been shown to promote cell proliferation and induce osteogenic differentiation; however, its specific effects on ADSC osteogenesis and the mechanisms by which ICA enhances osteoporosis treatment through cell transplantation remain inadequately understood.