METTL1 mediates PKM m7G modification to regulate CD155 expression and promote immune evasion in colorectal cancer.

Background: Colorectal cancer (CRC) is characterized by poor responsiveness to immune evasion and immunotherapy. RNA 7-methylguanine (m7G) modification plays a key role in tumorigenesis. However, the mechanisms by which m7G-modified RNA metabolism affects tumor progression are not fully understood, nor is the contribution of m7G-modified RNA to the CRC immune microenvironment.

Improved bacterial cellulose production by Acetobacter oryzoeni MGC-N8819 in tobacco waste extract coupled with nicotine removal by Pseudomonas sp. JY-Q/5∆.

As the substrate, tobacco waste extract (TWE) can produce bacterial cellulose (BC), a biobased material. However, nicotine inhibits BC production (adding 0.8 g/L nicotine to the HS medium had a negative effect on BC synthesis) and needs to be removed.

Policy effects of reduced pension contribution rate on innovation input--Empirical evidence from Zhejiang and Shandong provinces.

Reducing pension insurance rates is an important measure for lowering the burden on enterprises. Does this measure encourage enterprises to invest in innovation? This study uses provincial panel data of China during 2000-2017 to analyze the reduction in the proportion of enterprise contributions to pension insurance in Zhejiang and Shandong provinces as a quasi-natural experiment. Specifically, it uses the synthetic control method to construct a counterfactual state of the treatment group, and analyzes the effect of fee reduction policy on enterprise innovation input.

Enhancing Respiration Function Evaluation and Recovery in Lung Cancer: The Interdisciplinary Approach to Postoperative Management.

We highlight the potential for further analysis and investigation of the article by Sirakaya and colleagues. Specifically, we note that the authors failed to evaluate diaphragm mobility, which is essential for a comprehensive assessment of respiratory function, as well as diaphragm thickness. Assessing diaphragm mobility could enrich our understanding of the impact of surgical approaches on respiratory mechanics and postoperative pulmonary complications.

Robust ferromagnetism in wafer-scale FeGaTe above room-temperature.

The discovery of ferromagnetism in van der Waals (vdW) materials has enriched the understanding of two-dimensional (2D) magnetic orders and opened new avenues for fundamental physics research and next generation spintronics. However, achieving ferromagnetic order at room temperature, along with strong perpendicular magnetic anisotropy, remains a significant challenge. In this work, we report wafer-scale growth of vdW ferromagnet FeGaTe using molecular beam epitaxy.