Publications by authors named "Z H Cen"
Various electrochemical tests were carried out to elucidate the electrolytic oxidation mechanism of oxalic acid on a boron-doped diamond electrode in a nitric acid environment. These included cyclic voltammetry, AC impedance, constant current electrolysis, and electron paramagnetic resonance spectroscopy. The impact of electrode potential, current density, nitric acid concentration, and electrode plate spacing on the oxidation of oxalic acid was investigated.
View Article and Find Full Text PDFLupeol, a naturally occurring triterpenoid, has garnered significant attention for its diverse range of biological activities and potential therapeutic applications. This comprehensive review delves into the various aspects of lupeol, including its sources, extraction methods, chemical characteristics, pharmacokinetics, safety evaluation, mechanisms of action, and applications in disease treatment. We highlight the compound's unique carbon skeleton and its role in inflammation regulation, antioxidant activity, and broad-spectrum antimicrobial effects.
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- Intracerebral calcium deposition includes primary familial brain calcification (PFBC), which leads to motor decline, speech difficulties, and cognitive issues, with limited treatment options available.* -
- Recent findings link PFBC to blood-brain barrier dysfunction, influenced by genetic variants that affect the neurovascular unit (NVU), leading to brain calcification.* -
- The review examines literature on genetic mutations in cell junction proteins related to brain calcification, aiming to identify molecular pathways and support the need for molecular subtyping in understanding this condition.*
Lethal COVID-19 outcomes are attributed to classic cytokine storm. We revisit this using RNA sequencing of nasopharyngeal and 40 autopsy samples from patients dying of SARS-CoV-2. Subsets of the 100 top-upregulated genes in nasal swabs are upregulated in the heart, lung, kidney, and liver, but not mediastinal lymph nodes.
View Article and Find Full Text PDFBackground: Low parental awareness and knowledge about newborn screening have been identified as a public issue. This study explored Chinese parents' self-evaluation of awareness, knowledge, and methods of receiving information about newborn screening.
Methods: Using convenience sampling, we included 614 respondents who were expectant parents or parents of children aged 0-3 years.