Peri-Operative Hypothermia in Trauma Patients: A Retrospective Cohort Analysis at a Busy District General Hospital Within the National Health Service (NHS).

Introduction:  Perioperative hypothermia is defined as a patient's core body temperature of less than 36°C, which can lead to several complications. Even mild hypothermia increases the incidence of post-operative wound infection, post-operative ischaemic cardiac events and intra-operative blood loss and prolongs post-operative recovery. It is, hence, essential to maintain and provide normothermia during the perioperative phases for optimal surgical results and patient satisfaction.

Displaced Pediatric Supracondylar Fracture (Gartland Type II and III): The Impact of Wire Fixation Type.

Introduction Supracondylar fractures are common in children. Percutaneous K-wire fixation is an accepted standard treatment for displaced supracondylar fractures in children, but the ideal wire configuration remains controversial. This study aimed to review the radiographic outcome and complications of Gartland type II and type III supracondylar fractures treated by the crossed and lateral K-wire fixation.

Challenges and prospects of clinical trials in Nigeria - Lessons from the WHO COVID-19 solidarity plus trial.

Conducting randomized clinical trials (RCTs) during a pandemic is essential for obtaining timely evidence on safe and effective treatments, but it presents numerous obstacles. During the COVID-19 pandemic, the World Health Organization (WHO) sponsored multinational RCTs investigating repurposed drugs among hospitalized COVID-19 patients across countries with varying clinical research capacities. In Nigeria, several challenges hindered our progress, including inadequate infrastructure, initial insufficient investigator certification and expertise, and delays in securing regulatory approvals due to bureaucratic hurdles.

Antibiotic resistance and serotype distribution of strains in Bangladesh over the period of 2014-2022: evidence from a nationwide hospital-based surveillance for cholera and other diarrheal diseases.

Unlabelled: The objective of this study was to assess the prevalence, antimicrobial resistance patterns, and risk factors linked to infections through a nationwide hospital-based diarrheal disease surveillance in Bangladesh. From May 2014 to May 2022, from a systematic sentinel surveillance of infections in over 10 hospitals across Bangladesh, stool specimens were collected from patients with acute watery diarrhea and tested for species by microbiological culture. The susceptibility to antibiotics was tested using the disk diffusion method.

PATTERN OF MORBIDITY OF PATIENTS ADMITTED TO NIGERIAN TERTIARY-LEVEL HOSPITALS: INSIGHTS FROM THE MOHOPA STUDY.

Background: There is a paucity of nationally representative data on the pattern of morbidity of hospitalised medical patients in Nigeria. We hereby provide insights from the MOHOPA (Pattern of Morbidities, Mortality and Healthcare Financing of Hospitalised Medical Patients in Hospitals) study on the pattern of morbidity among patients admitted to the medical wards of Nigerian tertiary-level hospitals.

Methods: At least 100 patients admitted to the medical and emergency wards of 7 tertiary-level hospitals, spread across the 6 geopolitical zones of Nigeria and the Capital City of Abuja, were consecutively recruited to join the study after obtaining written informed consent.