The effect of intraoperative radiotherapy in musculoskeletal malignancy: A population study from US SEER database.

The aim of our study was to explore the effect of IORT on survival outcome of patients with musculoskeletal malignancy. The prognostic factors of patients with IORT treatment were also identified in this study. The retrospective analysis was conducted based on the Surveillance, Epidemiology, and End Results (SEER) database spanning from 2000 to 2020.

Genome-wide identification and expression analysis of the gene family in pea.

Peas ( L.) serve as a vital model for plant development and stress research. The () gene family, encoding essential motor proteins, remains understudied in peas.

Boosting Electrocatalytic Nitrate Reduction to Ammonia on a Hierarchical Nanoporous Ag,Ni-Codoped Cu Catalyst via Trimetallic Synergistic and Nanopore Enrichment Effects.

The electrochemical nitrate (NO) reduction reaction (NORR) offers a promising route for NO wastewater treatment and sustainable ammonia (NH) synthesis. However, the reaction still faces the challenges of unsatisfactory productivity and selectivity. Herein, we report a hierarchical nanoporous Ag,Ni-codoped Cu (np Ag,Ni-Cu) catalyst that exhibits a high NH Faradaic efficiency of 98.

The Effects of Perioperative Corticosteroids on Postoperative Complications After Pancreatoduodenectomy: A Debated Topic of Systematic Review and Meta-analysis.

Background: The intraoperative administration of corticosteroids has been shown to improve postoperative outcomes in patients undergoing surgery; however, the impact of corticosteroids on complications following pancreatoduodenectomy (PD) remains controversial.

Objective: This study aimed to evaluate the efficacy of perioperative corticosteroids on postoperative complications after PD.

Materials And Methods: A comprehensive search was conducted using the PubMed, Embase, and Web of Science databases for studies published prior to 1 July 2024.

Sulfur dioxide increases testosterone biosynthesis by activating ERK1/2 pathway and disrupting autophagy in Leydig cells.

Sulfur dioxide (SO) is a ubiquitous environmental pollutant that has been shown to be toxic to the male reproductive system, but the underlying mechanism remains unclear. Therefore, the SO-treated mice and primary Leydig cell models were established to investigate the effects of SO on the production of testosterone and its specific mechanism. The results demonstrated that SO activated the ERK1/2 signaling pathway, leading to increased key proteins expression of testosterone biosynthesis and elevated testosterone levels.