Publications by authors named "Z Endre"

Article Synopsis
  • Heart failure is prevalent among hemodialysis patients, and high flow arteriovenous fistulas (AVFs) may be a risk factor; this study aims to create a predictive model to identify patients at risk of developing high flow AVFs.
  • Using data from 366 patients, the study compared various machine learning models to predict high flow AVF development, finding that the bootstrap forest model was the most effective.
  • Results showed that while 31.4% of patients had high flow AVFs, and 24.9% developed heart failure after AVF creation, no direct correlation was found between AVF flow and the onset of heart failure or death post-creation.
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Background: Chronic kidney disease (CKD) is a significant clinical challenge in Sri Lanka. The present study presents histopathological diagnoses from native renal biopsies in Kandy District, 2011-2020.

Methods: Reports of 5,014 renal biopsies principally performed at Kandy Teaching Hospital over 2011-2020 were reviewed.

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Article Synopsis
  • Calcium-sensing receptors (CaSRs) are critical in regulating calcium levels and hormone release related to calcium metabolism by acting in the kidneys, gut, and bones.
  • Genetic variations, particularly single nucleotide polymorphisms in CaSR genes, can lead to various conditions affecting calcium balance, such as autosomal dominant hypercalciuric hypocalcaemia.
  • A case study highlights a female patient who developed severe kidney issues after treatment for hypocalcaemia in childhood, but post-kidney transplant, her condition improved and she now has stable calcium and phosphate levels.
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