Publications by authors named "Z Elkarhat"

Article Synopsis
  • Camel contagious ecthyma is a viral skin disease that significantly impacts camels and leads to economic losses; this study focuses on identifying and analyzing the virus in Morocco, where it was found in 4 out of 15 affected camels.
  • The research involved isolating the virus from skin crust samples and conducting various tests including PCR, which identified genetic similarities to the Ethiopian strain and allowed classification into two genetic clades: Asian and African lineages.
  • This study marks the first detection of the virus in North Africa and highlights the virus's opportunistic infection tendencies linked to stress in the animals, suggesting the need for further research to assess its behavior and help in vaccine development.
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Article Synopsis
  • Contagious ecthyma (CE), also known as ORF, is a viral skin disease affecting humans and various animals, including sheep and goats.
  • A study investigating an outbreak of sheeppox and ORF in Northwest Morocco identified skin lesions in affected sheep and confirmed ORF through PCR testing.
  • This research marks the first detection of ORF in Morocco, highlighting a potential health risk for humans and animals alike.
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Prevention and control of camelpox can be achieved by efficient vaccination. A limited number of homologous attenuated vaccines have been commercialized. In this study, we report the draft genome sequence of camelpox virus vaccine strain "CAMPOX vaccine" after 175 passages of attenuation in Vero cells.

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The process of steroidogenesis plays a vital role in human physiology as it governs the biosynthesis of mineralocorticoids, glucocorticoids, and androgens. These three classes of steroid hormones are primarily produced in the adrenal and gonadal glands through steroidogenesis pathways. Initiated by the side chain cleavage of cholesterol (CLR), this process leads to the conversion of cholesterol into pregnenolone and isocaproic aldehyde.

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