Publications by authors named "Z Depuis"

We report a case of severe pancytopenia in a 15-year-old patient due to a severe deficiency in vitamin B12 and folic acid, probably of nutritional origin. The clinical and biological course was favorable after vitamin supplementation. With this case, we discuss the diagnostic approach of pancytopenia with megaloblastic anemia in children and adolescents, as well as the mechanisms involved in vitamin B12 and B9 deficiency.

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Among the somatic and medical consequences of the pandemic linked to COVID-19, the increase in the rate of domestic violence and child abuse is one of the most serious and significant encountered in pediatrics. Indeed, if the reporting rate of ill-treatment of minors was abnormally low during the confinement of March-May 2020, the reopening of schools and psycho-social intervention teams in the spring made it possible to highlight a signifi¬cant increase in the number of worrying clinical situations. In some cases that meet strict hospitalization criteria, the social services call on specialized teams to take care of child victims of abuse.

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Invasive Group A Streptococcus infections and streptococcal toxic shock syndrome are rare complications of common diseases in children such as scarlet fever or impetigo. These invasive diseases are particulary challenging because of their rapid progression and the lack of predisposing factors in most cases. Prompt diagnosis and treatment are mandatory to reduce the mortality associated with these severe diseases.

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