Impact of the Luding Earthquake on the Area of Potentially Suitable Habitat for Species in the Gongga Mountain National Nature Reserve.

Members of the genus are endemic to China and include seven described species, five of which are nationally protected salamanders in China. The Gongga Mountain National Nature Reserve (GGMNNR) is rich in animal and plant resources, including the species. On 5 September 2022, the GGMNNR experienced the Luding earthquake, and this provided an opportunity to quantify the impact of a catastrophic events on the area of potentially suitable habitat for a rare species in the GGMNNR.

Consensus representation of multiple cell-cell graphs from gene signaling pathways for cell type annotation.

Background: Recent advancements in single-cell RNA sequencing have greatly expanded our knowledge of the heterogeneous nature of tissues. However, robust and accurate cell type annotation continues to be a major challenge, hindered by issues such as marker specificity, batch effects, and a lack of comprehensive spatial and interaction data. Traditional annotation methods often fail to adequately address the complexity of cellular interactions and gene regulatory networks.

Identify and analyze ferroptosis-related molecular modules and immune signatures in epilepsy using microarray-based transcriptome profiling and single-cell sequencing.

Currently, the pathogenesis of epilepsy remains poorly understood. Although there is evidence indicating that iron death might play a significant role, its molecular immunological mechanisms are largely unknown. This study was designed to analyze and explore the molecular mechanisms and immunological characteristics of iron death-related genes in epilepsy.

One-step fabrication of ultrathin porous Janus membrane within seconds for waterproof and breathable electronic skin.

It remains a challenge for a simple and scalable method to fabricate ultrathin porous Janus membranes for stretchable on-skin electronics. Here, we propose a one-step droplet spreading phase separation strategy to prepare an ultrathin and easily collected Janus thermoplastic polyurethane (TPU) membrane within seconds. The metal-ion solvation structure mitigated migration kinetics to delay TPU solution demixing, promoting the further penetration of the coagulating solvent.

Predicting circRNA-Disease Associations through Multisource Domain-Aware Embeddings and Feature Projection Networks.

Recent studies have highlighted the significant role of circular RNAs (circRNAs) in various diseases. Accurately predicting circRNA-disease associations is crucial for understanding their biological functions and disease mechanisms. This work introduces the MNDCDA method, designed to address the challenges posed by the limited number of known circRNA-disease associations and the high cost of biological experiments.