[Use of etoposide, ifosfamide and cisplatin (EIP) for treatment of inoperable non-small cell lung cancer].

Recent studies have pointed out that chemotherapy can prolong life in advanced inoperable cancer patients. A clinical study to evaluate response and toxicity of the combination of etoposide, ifosfamide and cisplatin (EIP) in the treatment of inoperable non-small cell lung cancer was performed. 25 patients entered the study.

[Prognostic factors and results of treating 42 patients with nln-seminomatous germ cell tumor of the testis].

In 1984-1988, 42 patients with non-seminomatous germ-cell tumour of the testis were treated surgically in combination with chemotherapy. Actually, 21 (50%) patients live without any symptoms, 5 (12%) patients with the symptoms during treatment whereas 6 (38%) patients died. Survival period of cured patients was 10-50 months (median 29 months) while still treated patients--5-34 months (median 10 months).

[Comparison of the cytotoxic activity of doxorubicin and epirubicin by an in vitro test].

In a group of 34 tumours representing 9 various human neoplasms the cytotoxic activity was compared of doxorubicin (Adriamycin) and epirubicin (Farmorubicin) in vitro. The method was based on measurements of the degree of inhibition of 3H-uridine incorporation in a suspension of cells of the tumour incubated with the cytostatic agent as compared to the activity in the control group. In 7 cases (21%) the tumours were sensitive to both agents, 26 tumours (76%) failed to respond to either drug.