The object of this study was to find out, by means of statistical-mathematical methods, whether the serum concentrations of Zn and Cu had a role in the interrelation among immunoglobulins IgA, IgM, IgG in four groups of subjects with various forms of liver diseases. It was found that the correlation structure between IgA, IgM, IgG and the serum concentration of Zn or Cu were different in the four types of diseases studied, and also that of these two metal ions, Zn was the most important, influencing the interdependence between the immunoglobulins in the active forms of disease.
View Article and Find Full Text PDFRom J Intern Med
December 1996
The variations of serum zinc concentration were studied in acute and chronic hepatitis of various etiologies. Coefficients of correlation were found with serum immunoglobulins and alanine aminotransferase (ALAT). The data obtained suggest the possible utilization of these coefficients in the estimation of prognosis in acute and chronic liver diseases.
View Article and Find Full Text PDFThe zinc, an important enzymatic cofactor, is involved in many metabolic processes. Its deficiency might be due either to malabsorption or to excessive utilization. In the medical literature of the latest 10 years, zinc was considered to play a part in the immune processes.
View Article and Find Full Text PDFThe interdependence between the serum Zn, Ca, Mg concentrations was studied in a group of healthy subjects comparatively with a group of patients with various form of cancer. It was found that it is significant difference between the control group and the groups of cancer patients, which shows that the carcinogenic processes disturb the concentrations of these metallic ions, not only quantitatively but also the interdependence between them.
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February 1993
The serum copper and zinc concentration, the Cu/Zn ratio and ceruloplasmin activity have been studied in 400 subjects divided into 4 groups of study: 50 normal subjects (controls), 100 patients with ischemic heart disease, 100 subjects with myocardial infarction in the past history and 150 patients with acute myocardial infarction. It was observed that in normal subjects the Cu/Zn ratio is about 1, in acute myocardial infarction it reaches 2.5 but it returns to normal during convalescence.
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