Introduction: While many studies have been published on Ultrasound-guided regional anesthesia in the Emergency Department (ED), there has been no previous study assessing the current state of the literature based in the form of a scoping review.
Objective: The purpose of this study is to evaluate the current state of the literature on UGRA performed in the ED setting.
Methods: EMBASE, MEDLINE, CINAHL, and Cochrane databases were searched for studies.
The peroxisome proliferator-activated receptor gamma (PPARγ) regulates osteoblast and osteoclast differentiation, and is the molecular target of thiazolidinediones (TZDs), insulin sensitizers that enhance glucose utilization and adipocyte differentiation. However, clinical use of TZDs has been limited by side effects including a higher risk of fractures and bone loss. Here we demonstrate that the same post-translational modifications at S112 and S273, which influence PPARγ pro-adipocytic and insulin sensitizing activities, also determine PPARγ osteoblastic (pS112) and osteoclastic (pS273) activities.
View Article and Find Full Text PDFBeitr Klin Tuberk Spezif Tuberkuloseforsch
November 1998