Rev Assoc Med Bras (1992)
May 2024
Objective: Cellular and humoral immunity plays a role in the pathogenesis of vitiligo. T lymphocytes and natural killer cells involved in cellular immunity carry out their cytotoxic activities through perforin/granzyme-dependent granule exocytosis, in which granulysin and cathepsin-L are also involved. The aim of this study was to investigate the possible role of serum granulysin and cathepsin-L in the etiopathogenesis of vitiligo and their association with disease activity and severity.
View Article and Find Full Text PDFObjectives: To investigate the effects of increasing propolis doses on salivary glands exposed to radiotherapy (RT).
Methods: Thirty-seven rats were divided into 4 groups: The control group (G0, n: 7), G1 group (n: 10), G2 group (n: 10), and G3 group (n: 10). The rats in the G1 group received 15 Gray (Gy) RT only to the head and neck area.
Rev Assoc Med Bras (1992)
November 2023
Objective: The delayed increase in serum creatinine levels poses challenges in the timely diagnosis of acute kidney injury. This study aimed to investigate the relationship between serum angiotensinogen and urinary angiotensinogen levels and the prognosis of renal function in patients diagnosed with acute kidney injury.
Methods: A total of 79 newly diagnosed acute kidney injury patients aged 18 years and older were enrolled.
Introduction: Malignant pleural effusion (MPE) and lymph node metastasis (LNM) presence are poor prognostic factors that have importance for cancer patients. The study objective was to determine whether hypoxia-inducible factor-1α (HIF-1α) and prominin-1 (CD133) in pleural fluid (P) and serum (S) could be used as biomarkers for diagnosis of lymph node involvement in patients with MPE.
Materials And Methods: Fifty-six patients with MPE and 30 healthy control subjects were included.
Objective: The aim of our study was to analyze the radiologic morphometry of the distal radius and wrist to assess acceptable limits for restoring normal wrist function after fracture.
Methods: Radiological measurement parameters were measured retrospectively on anteroposterior and lateral (LAT) wrist radiographs (n=981). Radiological measurement parameters were volar tilt, radial inclination, radial height, ulnar variance, radiocarpal angle, and volar angulation angle.