Publications by authors named "Z Brassai"

Article Synopsis
  • Peripheral arterial disease (PAD) is related to atherosclerosis in other arterial regions and is linked to serious cardiovascular risks and high mortality rates.
  • In a study of 90 PAD patients, higher levels of Cystatin C (Cys C) and a lower Cathepsin S (Cat S) to Cys C ratio were found to correlate with more severe stages of PAD, as indicated by low ankle-brachial index (ABI) scores.
  • The findings suggest that elevated Cys C and decreased Cat S/Cys C ratios may serve as important indicators of severe PAD and the presence of multiple arterial blockages.
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Article Synopsis
  • The study examines the relationship between AB0 blood groups, osteoprotegerin (OPG), and von Willebrand factor (VWF) levels in patients with peripheral arterial disease (PAD).
  • Results showed that OPG levels were significantly higher in PAD patients compared to controls, especially in those with critical limb ischemia.
  • Additionally, OPG levels positively correlated with VWF levels and were notably elevated in non-O blood group individuals, suggesting a link between blood type and disease severity in PAD.
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Aim: The aim of this study was to evaluate the dynamics of the recanalization process (spontaneous fibrinolysis) in completely occlusive deep venous thrombosis (DVT) using duplex ultrasound examination and to investigate the influence of different factors on the evolution of thrombus regression.

Methods: This longitudinal prospective study was done with 74 consecutive patients with completely occlusive acute multilevel DVT, confirmed by echo duplex scan after 1, 3, 6, and 12 months. At each re-evaluation, the degree and the type of recanalization were determined.

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The efficacy of dextran therapy in forty patients with chronic occlusive arterial disease (twelve with Buerger's disease and twenty-eight with atherosclerosis obliterans) was studied by repeated measurements of the following hemodynamic parameters;: the relative walking distance (RWD), the absolute walking distance (AWD), the oscillometric index (OI), the perfusion pressure of the affected limb (PP) and the Doppler index (DI) - the last two being determined by using an ultrasound technique. The hemodynamic improvements secondary to dextran therapy were demonstrated by the increase of RWD (from 115.3 m to 235.

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