Publications by authors named "Z B Perkins"

Introduction: Both predictions and performance of clinical predictive models can be presented with various verbal and visual representations. This study aims to investigate how different risk and performance presentations for probabilistic predictions affect clinical users' judgement and preferences.

Methods: We use a clinical Bayesian Network (BN) model that has been developed for predicting the risk of Trauma Induced Coagulopathy (TIC).

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Background: The primary aim of this scoping review was to synthesise key domains and sub-domains described in existing clinical decision support systems (CDSS) implementation frameworks into a novel taxonomy and demonstrate most-studied and least-studied areas. Secondary objectives were to evaluate the frequency and manner of use of each framework, and catalogue frameworks by implementation stage.

Methods: A scoping review of Pubmed, Scopus, Web of Science, PsychInfo and Embase was conducted on 12/01/2022, limited to English language, including 2000-2021.

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Article Synopsis
  • Higher preoperative HDL levels can reduce the risk of acute kidney injury (AKI) after major cardiac and vascular surgery, likely due to its anti-inflammatory properties.
  • A study involving 100 adults with chronic kidney disease on statins found that those with dysfunctional, pro-inflammatory HDL had a significantly higher rate of AKI post-surgery.
  • The ability of HDL to suppress inflammatory markers in the blood was shown to be a better predictor of AKI than HDL concentration alone, suggesting that the quality of HDL matters more than just its quantity.
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  • * There is hope, as some people can survive TCA and recover well with the right treatment right away.
  • * The HOTT protocol helps doctors focus on fixing issues like low blood volume and lack of oxygen, while advanced methods can make treatment even better.
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