Publications by authors named "Z Ayed"

is a remarkable microorganism known for its diversity of habitat and its multi-drug resistance, resulting in hard-to-treat infections. Thus, a sensitive method for the identification and detection of is vital. However, current methods used for the detection of pathogens have not improved in the past decades and suffer from long process times and low detection limits.

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Quantum dots are attractive alternatives to organic fluorophores for the purposes of fluorescent labeling and the detection of biomarkers. They can also be made to specifically target a protein of interest by conjugating biomolecules, such as antibodies. However, the majority of the fluorescent labeling using quantum dots is done using toxic materials such as cadmium or lead due to the well-established synthetic processes for these quantum dots.

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Article Synopsis
  • The TRIM14 protein is involved in both antiviral defense and cancer processes, affecting apoptosis in different ways depending on the type of tumor cells.
  • A study investigated the role of human TRIM14 and its mutant form in inducing apoptosis in transgenic loach embryos, revealing increased apoptosis associated with both forms of the gene.
  • The findings suggest that TRIM14 promotes cell death during embryonic development through the activation of certain proapoptotic genes, with the mutant version following a different, p53-independent pathway.
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In stage II human african trypanosomiasis (HAT), which is characterized by central nervous system (CNS) involvement, neurones and oligodendrocytes might be targets of dysimmune processes. Nitric oxide (NO) production by peripheral macrophages is documented in HAT. We studied the production of NO by murine astrocytes and microglia cocultured with Trypanosoma brucei (T.

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