Publications by authors named "Z Al-Wahab"

Article Synopsis
  • Ovarian cancer is a highly lethal gynecologic cancer, often diagnosed at late stages due to its asymptomatic nature, highlighting the need for non-invasive diagnostic methods.
  • The study utilized AI and genome-wide analysis of circulating tumor DNA to detect epithelial ovarian cancer, uncovering significant epigenetic changes in DNA methylation across various markers.
  • The results showed high diagnostic accuracy with conventional regression and multiple AI platforms, achieving an area under the ROC curve of up to 1.00, while also identifying key molecular pathways linked to the disease's pathogenesis.
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Purpose: This study aimed to evaluate outcomes and toxicity in patients with endometrial cancer per our institutional adjuvant vaginal cuff brachytherapy (VBT) fractionation scheme.

Methods And Materials: We identified women with International Federation of Gynecology and Oncology stages I and II endometrial cancer who underwent surgical staging and adjuvant high-dose-rate VBT without external beam radiation. All patients received 30 Gy in 6 fractions to the upper one-third of the vagina, prescribed to a depth of 5 mm and delivered twice weekly.

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Aggressive angiomyxoma (AA) is a rare mesenchymal tumour that is characterised by increased incidence in women compared with men, local invasion to the surrounding tissue and high recurrence rate. A premenopausal woman presented to clinic with pelvic pressure, intermittent tingling in the thigh and pressure emptying the bladder. CT scan, vaginal and gluteal biopsies, and MRI scan were performed to conclude a final diagnosis of AA.

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Purpose: After definitive surgery, women with early-stage, low-risk endometrial cancer are observed. However, some will require salvage radiation therapy for recurrence. The purpose of this study was to evaluate our experience using salvage radiation for recurrent endometrial cancer in patients who did not receive upfront adjuvant therapy.

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