Mechanisms and causes of hypomagnesemia.

Purpose Of Review: Identification of the mechanisms of magnesium absorption and reabsorption has markedly enhanced our understanding of the causes of hypomagnesemia.

Recent Findings: New gastrointestinal and renal causes of hypomagnesemia have been recently documented.

Summary: The recognition of new mechanisms and causes of magnesium absorption and reabsorption should enhance the ability to monitor patients at risk for hypomagnesemia and improve our ability to mitigate the serious symptoms associated with this disorder.

Commentary: CME and its role in the academic medical center: increasing integration, adding value.

Continuing medical education (CME), as it is currently structured, funded, and institutionalized, plays a marginal role in the academic medical center (AMC). In contrast, several models of more effective, integrated CME exist, and these enable the AMC to better achieve its potential in education, research, and health care delivery. Examples of such models are presented, emphasizing quality and performance improvement; regional, national, and public outreach; faculty and staff development; and research and scholarly activity.

Dietary intake and the risk of coronary heart disease among the coconut-consuming Minangkabau in West Sumatra, Indonesia.

Several nutrition and non-nutritional pathways are recognised in the development and occurrence of cardiovascular disease. In many populations, high intakes of saturated fat are associated with elevated serum cholesterol concentrations and increased coronary heart disease (CHD) mortality. However, several studies report that hyperlipidaemia and heart diseases are not common among populations who consume coconut, a source of saturated fat.

Pseudohyperphosphatemia in a hyperphosphatemic hemodialysis patient.

Hyperphosphatemia is a predictable consequence of end-stage renal disease. Pseudohyperphosphatemia is a spurious elevation of serum phosphate in samples containing a substance that interferes with the laboratory assay for phosphate. The most common cause is a paraprotein in disorders such as Waldenström's macroglobulinemia and multiple myeloma.

Contemporary Minangkabau food culture in West Sumatra, Indonesia.

Diet has a strong relationship with food culture and changes in it are likely to be involved in the pathogenesis of newly emergent degenerative diseases. To obtain in-depth opinions about the food culture of Minangkabau people, focus group discussions were conducted in a Minangkabau region, represented by four villages in West Sumatra, Indonesia, from January to March 1999. The members of the discussion groups were principally women aged from 35 to 82 years old.