Publications by authors named "Z Abedi"

Article Synopsis
  • Monkeypox (Mpox) is increasingly recognized as a public health issue, and this study uses multi-omics approaches to find therapeutic targets and drug repurposing opportunities to understand its molecular mechanisms.
  • Researchers created a host-pathogen interaction network and identified 55 differentially expressed genes related to Mpox, pinpointing 16 potential drug targets that include both proviral and antiviral genes involved in critical signaling pathways.
  • Promising FDA-approved drug candidates, such as kinase inhibitors and Niclosamide, were identified, aiming to enhance treatment strategies and further the understanding of Mpox's pathology.
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The health sector is one of the components of development, social welfare and economic growth. The purpose of this study was to develop an economic evaluation model of the environmental and health costs of occupational diseases by hybrid approach. To achieve the study goal, a taxonomy of economic evaluation model of the environmental and health costs of occupational diseases has been developed.

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Glaucoma is the second leading cause of irreversible blindness, and primary open-angle glaucoma (POAG) is the most common type. Due to inadequate diagnosis, treatment is often not administered until symptoms occur. Hence, approaches enabling earlier prediction or diagnosis of POAG are necessary.

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The abundance of biomedical knowledge gained from biological experiments and clinical practices is an invaluable resource for biomedicine. The emerging biomedical knowledge graphs (BKGs) provide an efficient and effective way to manage the abundant knowledge in biomedical and life science. In this study, we created a comprehensive BKG called the integrative Biomedical Knowledge Hub (iBKH) by harmonizing and integrating information from diverse biomedical resources.

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