[Action of red polarized light on the acupuncture point E-36 increases analgesic effect of corvitin].

In experiments on mice of lines C57BL/6J and CBA/CaLac, the possibility of strengthening of analgesic effect of corvitin by the action of red polarized light (PL) on the acupoint (AP) E-36 was studied. The pain behavioral response (licking of the painful area) was caused by injection of 5% formalin in hind limb (0.25 microl subcutaneously).

Antinociceptive effects of color polarized light in animal with formalin test.

Our recent results show the efficacy of pain suppression by exposure of antinociceptive acupuncture points (APs) to white polarized (P) light. But it is known that white light contains electromagnetic waves of different length (colors) and, possibly, not all of them produce a similar effect. There are no comparative data about analgesic affects of the different colors of P light now.

[Influence of korvityn on somatic pain in mice of different genotypes].

The influence of the intraperitoneal injection of quercetin solution (10 mg/kg) on painful reaction to the formalin test in male mice C57B1/6J (C57), CBA/CaLac (CBA) and in outbred albino mice was investigated. It was shown, that quercetin caused a various level of analgesia in the investigated animals. The highest level of analgesia (38,5 %) was observed in outbred white mice, the average - in mice C57 (27%) and the lowest - in mice CBA (13%).

Influences of sensory input from the limbs on feline corticospinal neurons during postural responses.

The dorsal-side-up body posture of standing quadrupeds is maintained by coordinated activity of all limbs. Somatosensory input from the limbs evokes postural responses when the supporting surface is perturbed. The aim of this study was to reveal the contribution of sensory inputs from individual limbs to the posture-related modulation of pyramidal tract neurons (PTNs) arising in the primary motor cortex.

Role of GABA A inhibition in modulation of pyramidal tract neuron activity during postural corrections.

In a previous study we demonstrated that the activity of pyramidal tract neurons (PTNs) of the motor cortex is modulated in relation to postural corrections evoked by periodical tilts of the animal. The modulation included an increase in activity in one phase of the tilt cycle and a decrease in the other phase. It is known that the motor cortex contains a large population of inhibitory GABAergic neurons.