DDR2-regulated arginase activity in ovarian cancer-associated fibroblasts promotes collagen production and tumor progression.

Ovarian cancer has poor survival outcomes particularly for advanced stage, metastatic disease. Metastasis is promoted by interactions of stromal cells, such as cancer-associated fibroblasts (CAFs) in the tumor microenvironment (TME), with tumor cells. CAFs play a key role in tumor progression by remodeling the TME and extracellular matrix (ECM) to result in a more permissive environment for tumor progression.

Design and Evaluation of Structural Shielding of a Typical Radiotherapy Facility Using EGSnrc Monte Carlo Code.

Purpose: This study aimed to evaluate the shielding integrity of a typical radiotherapy facility using the Monte Carlo (MC) method.

Materials And Methods: EGSnrc MC code was used to design a radiotherapy bunker with appropriate materials and thicknesses. A concrete density of 2.

Reliability of Sonographic Estimation of Fetal Weight: A Study of Three Tertiary Hospitals in Nigeria.

Context: There is a dearth of sonologists in Nigeria, yet sonographic estimation of actual birth weight (ABW) is important in antenatal care.

Aim: To determine the reliability of estimated fetal weight (EFW) by sonographers and sonologists in Lagos Nigeria.

Settings And Design: In the cross-sectional study, a convenience sample of 663 healthy women with singleton pregnancy at term was selected.

Verification of Entrance Dose Measurements with Thermoluminescent Dosimeters in Conventional Radiotherapy Procedures Delivered with Co-60 Teletherapy Machine.

Background: The use of in vivo dosimetry with thermolumiscent dosimeters (TLDs) as a veritable means of quality control in conventional radiotherapy procedures was determined in this work.

Aim: The objective of this study was to determine the role of in vivo dosimetry with thermoluminescent dosimeters (TLDs) as part of quality control and audit in conventional radiotherapy procedures delivered with Co-60 teletherapy machine.

Subjects And Methods: Fifty-seven patients with cancers of the breast, pelvis, head and neck were admitted for this study.

Optimization of dual slot antenna using floating metallic sleeve for microwave ablation.

Backward heating reduction is vital in power distribution optimization in microwave thermal ablation. In this study, we optimized dual slot antenna to yield reduction in backward heating pattern along the antenna shaft with the application of floating metallic sleeve. Finite element methods were used to generate the electromagnetic (EM) field and thermal distribution in liver tissue.