Publications by authors named "Yvonne Wangui Machira"

Article Synopsis
  • South African adolescents are at high risk for HIV due to engaging in risky sexual behaviors, and effective communication between them and their caregivers is crucial for better decision-making.
  • A qualitative study involving 17 adolescents and 19 caregivers revealed that while adolescents had access to sexual education, their understanding did not lead to healthier choices, largely due to barriers in communication and support.
  • The study highlighted that female adolescents and caregivers could discuss sexual matters, but males faced discomfort and distrust, indicating the need for structured communication tools to facilitate these discussions and improve sexual health outcomes.
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Background: Structural, interpersonal and individual level factors can present barriers for HIV prevention behaviour among people at high risk of HIV acquisition, including women who sell sex. In this paper we document the contexts in which women selling sex in Kampala meet and provide services to their clients.

Methods: We collected qualitative data using semi-structured interviews.

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Region-specific laboratory reference intervals (RIs) are important for clinical trials and these data are often sparse in priority areas for research, including Africa. We reviewed data on RIs from Africa to identify gaps in the literature with a systematic review of PubMed for RI studies from Africa published ≥2010. Search focus included clinical analytic chemistry, hematology, immunological parameters and RIs.

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Background: There is limited information on factors that influence oral pre-exposure prophylaxis (PrEP) uptake and adherence among adolescent girls and young women (AGYW). We conducted a qualitative methods study to explore experiences, facilitators and barriers of PrEP uptake and adherence to PrEP among AGYW at risk of Human Immunodeficiency Virus (HIV) infection in Kampala, Uganda.

Methods: This study was nested in a prospective cohort study that offered daily oral PrEP to AGYW.

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Background: Sexual autonomy empowers women to set boundaries, take control of their bodies, prevent sexually transmitted diseases and avoid unplanned pregnancy. A woman's ability to negotiate safer sex is crucial for her survival and that of her child. Sexual autonomy among East African women is vital to the elimination of the deaths of neonates, infants, and children.

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