Publications by authors named "Yvonne Eberhardt"

Background: Recent developments suggest that neurosteroids may achieve rapid antidepressant effects. As such, neurosteroidogenesis mediated by the translocator protein 18 kDa (TSPO) might constitute a promising option for the treatment of depression. Therefore, the current clinical trial aims to get the first evidence of whether TPSO ligands promote rapid antidepressant effects.

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Article Synopsis
  • * The study, using a combination of ELISA and indirect immunofluorescence assays (iIFA), found varying reactivity rates for BoDV-1, but only one case confirmed positive for the virus, casting doubt on the overall reliability of initial screenings.
  • * Results suggest that no asymptomatic infections were present in the groups studied, and emphasize the importance of follow-up tests like iIFA for accurate diagnosis, as initial serological tests may yield false positives due to cross-reactivity.
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Objective: Limited data exist on the clinical benefits of nasal applications for moistening the nasal mucosa. We therefore investigated the effects of hyaluronic acid, hyaluronic acid plus dexpanthenol and isotonic saline nasal sprays in patients suffering from dry nose symptoms in an otorhinolaryngological outpatient setting.

Methods: 240 patients were randomised into this prospective, three-armed clinical trial with two assessment points (baseline and 4 weeks later).

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