Background: Levels of circulating hybrid cells (CHCs), a newly identified circulating tumor cell (CTC), correlate with disease stage and progression in cancer. We investigated their utility to risk-stratify patients with clinically N0 (cN0) oral cavity squamous cell carcinoma (OCSCC), and to identify patients with occult cervical lymph node metastases (pN+).
Methods: We analyzed peripheral blood samples for CHCs with co-expression of cytokeratin (tumor) and CD45 (leukocyte) from 22 patients with cN0 OCSCC using immunofluorescence microscopy, then correlated levels with pathologic lymph node status.
Background And Objectives: The Student Outreach Clinic (SOC) at the University of Nevada School of Medicine is one of several student-run free medical clinics associated with US medical schools. We report on the educational value of the SOC to medical students who volunteer at this clinic.
Methods: The records of all patients seen between August 1, 2012, and July 31, 2013, at the SOC were abstracted on a deidentified basis to collect key demographic and clinical components of the visit, including past medical history, components of the physical exam performed, clinical diagnoses recorded, patient disposition, and medications prescribed.