Publications by authors named "Yvette Montcho"

Since 2019, a new strain of coronavirus has challenged global health systems. Due its fragile healthcare systems, Africa was predicted to be the most affected continent. However, past experiences of African countries with epidemics and other factors, including actions taken by governments, have contributed to reducing the spread of SARS-CoV-2.

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Background: The Efficacy and effectiveness of vaccination against SARS-CoV-2 have clearly been shown by randomized trials and observational studies. Despite these successes on the individual level, vaccination of the population is essential to relieving hospitals and intensive care units. In this context, understanding the effects of vaccination and its lag-time on the population-level dynamics becomes necessary to adapt the vaccination campaigns and prepare for future pandemics.

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Article Synopsis
  • Several effective COVID-19 vaccines exist, but vaccination programs are limited in many African countries, prompting a study using a mathematical model to evaluate their impact on the pandemic.
  • The model focuses on two populations—vaccinated and unvaccinated—and assesses vaccine effectiveness by analyzing infection and death rate ratios, finding that at least 60% of each country’s population needs to be vaccinated to effectively lower the transmission rate of the virus.
  • The study suggests that even a slight reduction in transmission through non-pharmaceutical interventions can complement vaccination efforts, and calls for African governments to implement strategies to improve vaccine uptake, such as incentives.
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Introduction: Evaluating the potential effects of non-pharmaceutical interventions on COVID-19 dynamics is challenging and controversially discussed in the literature. The reasons are manifold, and some of them are as follows. First, interventions are strongly correlated, making a specific contribution difficult to disentangle; second, time trends (including SARS-CoV-2 variants, vaccination coverage and seasonality) influence the potential effects; third, interventions influence the different populations and dynamics with a time delay.

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