Publications by authors named "Yvette Kluiters"
Article Synopsis
- The study examined the impact of obesity on inflammatory biomarkers and clinical outcomes in critically ill patients with SARS-CoV-2 pneumonia.
- Among 105 patients, 42 were classified as obese, yet no significant differences in inflammatory markers (MR-proADM, CT-proET-1, etc.) were found between those with and without obesity over the first week of illness.
- The findings suggest that obesity does not affect the severity of inflammation or key clinical outcomes like ICU stay, ventilation time, or mortality in these cases.
Article Synopsis
- Aneurysmal subarachnoid hemorrhage (aSAH) is a serious condition that necessitates intensive care, and the study aimed to evaluate whether levels of C-terminal proarginine vasopressin (CT-proAVP) can predict poor outcomes, mortality, and delayed cerebral ischemia (DCI) in patients compared to existing scoring systems.
- The research examined CT-proAVP levels in 100 patients with aSAH and found that higher levels of CT-proAVP were significantly correlated with worse functional outcomes at one year, as well as with mortality within 30 days and one year.
- Though CT-proAVP showed high accuracy for predicting poor outcomes and mortality (with AUC values around 0.84
Purpose: We assessed the ability of mid-regional proadrenomedullin (MR-proADM) and C-terminal proendothelin-1 (CT-proET-1) to predict 28-day mortality in critically ill patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia.
Methods: Biomarkers were collected during the first seven days in this prospective observational cohort study. We investigated the relationship between biomarkers and mortality in a multivariable Cox regression model adjusted for age and SOFA score.
Background We assessed the ability of baseline and serial measurements of mid-regional proadrenomedullin (MR-proADM) and mid-regional proatrial natriuretic peptide (MR-proANP) to predict 28-day mortality in critically ill patients with pneumonia compared with Acute Physiological and Chronic Health Evaluation IV (APACHE IV) model and Sequential Organ Failure Assessment (SOFA) score. Methodology Biomarkers were collected for the first five days in this retrospective observational cohort study. Biomarker clearance (as a percentage) was presented as biomarker decline in five days.
View Article and Find Full Text PDFBackground: In critically ill patients, antibiotic therapy is of great importance but long duration of treatment is associated with the development of antimicrobial resistance. Procalcitonin is a marker used to guide antibacterial therapy and reduce its duration, but data about safety of this reduction are scarce. We assessed the efficacy and safety of procalcitonin-guided antibiotic treatment in patients in intensive care units (ICUs) in a health-care system with a comparatively low use of antibiotics.
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