Publications by authors named "Yves Lebouc"
French law: what about a reasoned reimbursement of serum vitamin D assays?
Geriatr Psychol Neuropsychiatr Vieil
December 2016
Article Synopsis
- Serum 25-hydroxyvitamin D (25OHD) tests in France have surged by tenfold over the past decade, often for questionable reasons.
- In 2013, the French National Authority for Health imposed limits on when these tests could be ordered, restricting them mainly to specific health conditions like rickets and certain cases in older adults.
- The authors argue that there are additional valid reasons for testing, supported by research, and advocate for the continued reimbursement of serum 25OHD tests for broader clinical scenarios.
Article Synopsis
- The study investigates the relationship between serum IGF-I levels and cognitive decline in Alzheimer's disease (AD) over a 24-month period.
- IGF-I and IGFBP-3 levels were measured in 200 AD participants, who underwent cognitive assessments (MMSE) every 6 months.
- Results showed that lower IGF-I levels correlated with a steeper decline in cognitive function, with participants having lower IGF-I losing more points on the MMSE annually.
[Weakening osteopathies, chronic kidney disease, malabsorption, biological anomalies of calium/phosphorus metabolism: appropriate indications for a reasoned reimbursment of serum vitamin D measurement].
Ann Biol Clin (Paris)
October 2015
Objective: Congenital cardiovascular malformations and aortic dilatation are frequent in patients with Turner syndrome (TS). The objective of this study was to investigate the cardiovascular findings and management in a large cohort of patients, including children and adults.
Design/methods: We recruited 336 patients with TS from a network of tertiary centers.
Purpose: To determine whether a single intra- or periarticular injection of corticosteroid for posttraumatic or microtraumatic articular injuries in young healthy subjects can induce a biological suppression of hypothalamo-pituitary-adrenal axis activity and reactivity.
Methods: Ten healthy young male athletes (aged 28.8 +/- 2.
A part of serum Ob leptin, an adipocyte-secreted peptide, is bound to a soluble Ob receptor (sObR). Immunoreactive sObR was measured in 125 lean or obese control subjects (group 1), 18 individuals with a mutation in the leptin gene impairing leptin secretion (group 2), and 10 individuals with a mutation in the ObR gene, leading to production of a truncated ObR not anchored to cell membranes (group 3). In group 1, sObR levels were negatively correlated with age and BMI in children and with BMI in adults.
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