Publications by authors named "Yuzu Abe"
J Antibiot (Tokyo)
July 2024
Article Synopsis
- Three new liposidomycin compounds (1, 2, and 4) were identified from the culture of a specific Streptomyces bacteria as potential treatments against Mycobacterium avium complex infections.
- The chemical structures of all liposidomycins, including new and known variants, were determined using techniques like NMR and MS analysis.
- The compounds demonstrated varying levels of effectiveness against M. avium and M. intracellulare, with minimal inhibitory concentrations (MIC) ranging from 2.0 to 64 μg/ml, and showed promising results in a silkworm infection model.
