Strategies to Improve Hydrolysis Efficiency of Fish Skin Collagen: Study on ACE Inhibitory Activity and Fibroblast Proliferation Activity.

Collagen peptides play a crucial role in promoting skin elasticity and enhancing joint health, with potential functions to be explored. Enzyme hydrolysis is crucial for the molecular weight and sequence of peptides, influencing the bio-activity. In this study, the angiotensin-converting enzyme (ACE) inhibitory activity and fibroblast proliferation activity of differentially molecular weight peptides derived from dual- or triple-enzyme hydrolysis were compared.

Predicting lncRNA-protein interactions with bipartite graph embedding and deep graph neural networks.

Long non-coding RNAs (lncRNAs) play crucial roles in numerous biological processes. Investigation of the lncRNA-protein interaction contributes to discovering the undetected molecular functions of lncRNAs. In recent years, increasingly computational approaches have substituted the traditional time-consuming experiments utilized to crack the possible unknown associations.