A Prediction Model for External Root Resorption of the Second Molars Associated With Third Molars.

Objectives: The aim of this study is to investigate risk factors for external root resorption (ERR) of second molars (M2) associated with impacted third molars (M3), and to develop a prediction model that can offer dentists a reliable and efficient tool for predicting the likelihood of ERR.

Methods: A total of 798 patients with 2156 impacted third molars were collected from three centres between 1 December 2018 and 15 December 2018. ERR was identified by cone beam computed tomography examinations.

Phlebitis in Takayasu arteritis: A case-based literature review.

Takayasu arteritis (TAK) is the main type of large vessel arteritis in young adults, which mainly affects the aorta and its main branches, leading to clinical manifestations such as syncope, intermittent limb claudication, hypertension, and abdominal pain. Among them, venous involvement is rarely reported. Here we show a case of TAK presenting as phlebitis.

Zinc Chelator N,N,N',N'-Tetrakis(2-Pyridylmethyl)Ethylenediamine Reduces the Resistance of to Imipenem.

Purpose: Imipenem is one of the very few effective options for treating () infections; the development of imipenem resistance is a major health concern.

Materials And Methods: The susceptibility of 194 clinical isolates to imipenem was determined. The ability of imipenem to synergize with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine (TPEN), a zinc chelator and a metallo-β-lactamases (MBLs) inhibitor, to inhibit growth was also assessed.

AR-12 Exhibits Direct and Host-Targeted Antibacterial Activity toward .

Therapeutic options for infections are extremely limited. New or repurposed drugs are needed. The anti- activity of AR-12 (OSU-03012), reported to express broad-spectrum antimicrobial effects, was investigated and Antimicrobial susceptibility testing was performed on 194 clinical isolates.

Genetic Evolution of Conferring Clarithromycin Resistance during Long-Term Antibiotic Therapy.

Objectives: Clarithromycin is recommended as the core agent for treating infections, which usually calls for at least one year of treatment course, facilitating the development of resistance. This study aimed to identify the underlying mechanism of development of clarithromycin resistance in clinical isolates.

Methods: isolates from patients with lung infections during long-term antibiotic therapy were longitudinally collected and sequenced.

Efflux Pumps Contribute to Intrinsic Clarithromycin Resistance in Clinical, Isolates.

Purpose: The emergence of clarithromycin resistance is a challenge in treating infections. Known mechanisms that contribute to intrinsic clarithromycin resistance focus on gene-related mutations, but resistant clinical isolates often exhibit an inconsistent genotype.

Patients And Methods: In this study, 194 clinical isolates were collected from patients with lung infections and the whole genome of each isolate was sequenced.

Detection and molecular characterisation of amikacin-resistant Mycobacterium abscessus isolated from patients with pulmonary disease.

Objectives: The aim of this study was to investigate the molecular mechanisms conferring amikacin (AMK) resistance in Mycobacterium abscessus clinical isolates.

Methods: A total of 194M. abscessus clinical isolates were collected from patients with pulmonary disease during the period 2012-2017.

Comparative study of the proliferative ability of skeletal muscle satellite cells under microwave irradiation in fractures with titanium alloy internal fixation in rabbits.

The aim of the present study was to investigate the proliferation of skeletal muscle satellite cells (MSCs) under different amounts of microwave irradiation in fractures with titanium alloy internal fixation. A total of 45 male New Zealand adult white rabbits were used to establish a femoral shaft fracture and titanium alloy internal fixation model. The rabbits were randomly divided into the control group (group A) and the experimental groups (groups B and C).

Molecular Analysis of Linezolid-Resistant Clinical Isolates of .

A total of 194 isolates were collected from patients, and the whole genomes were sequenced. Eighty-five (43.8%) isolates showed linezolid (LZD) resistance.

Clinical features of hypophosphatemic osteomalacia induced by long-term low-dose adefovir dipivoxil.

Objective: To investigate the predictors of hypophosphatemic osteomalacia induced by adefovir dipivoxil (ADV) and to monitor for early detection.

Patients And Methods: Hospitalized patients who were diagnosed with ADV-related hypo-phosphatemic osteomalacia were recruited and retrospectively analyzed in our hospital from January 2012 to December 2016. A telephone interview was conducted at 1, 3, 6, 9, 12, and 24 months after cessation of ADV.