Human Placental Mesenchymal Stem Cells-Exosomes Alleviate Endothelial Barrier Dysfunction via Cytoskeletal Remodeling through hsa-miR-148a-3p/ROCK1 Pathway.

Background: Endothelial barrier disruption of human pulmonary vascular endothelial cells (HPVECs) is an important pathogenic factor for acute lung injury (ALI)/acute respiratory distress syndrome (ARDS). Mesenchymal stem cells-exosome (MSCs-Exo) represents an ideal carrier for cell-free therapy. The therapeutic implication and underlying mechanism of human placental MSCs-Exo (HPMSCs-Exo) in ALI/ARDS need to be further explored.

Retrospective study of ovarian reaction and fertility in women with discordant antimullerian hormone and follicle-stimulating hormone/luteinizing hormone ratios during in vitro fertilization.

Objective: The objective of this study was to examine the predictive ability of follicle-stimulating hormone (FSH)/luteinizing hormone (LH) ratio and antimullerian hormone (AMH) levels in the same cohort when both are inconsistent and to identify which has an excellent ability to predict live birth and ovarian response to in vitro fertilization (IVF).

Methods: A retrospective cohort study was performed within 6096 IVF cycles executed between January 2016 and August 2019 at the Center for Assisted Reproduction, The Third Affiliated Hospital of Zhengzhou University, and Jiaozuo Maternity and Child Health Care Hospital. Initially, IVF cycles were classified according to basal FSH/LH ratio and AMH values, and the primary outcome was a comparison of live birth rate per cohort.

Prevention of omalizumab for seasonal allergic rhinoconjunctivitis: a retrospective cohort study.

Background: Allergic rhinoconjunctivitis (ARC) is an allergic disease that is characterized by conjunctival and nasal symptoms such as edema and congestion of conjunctiva, rhinorrhea, sneezing, and blocked nose. Seasonal ARC (SARC) is usually induced by seasonal allergens and often occurs at specific times during the year. Traditional treatments of SARC include nasal corticosteroids, antihistamines, and mast cell membrane stabilizers.

Remediation of arsenic-contaminated soil by nano-zirconia modified biochar.

Nowadays, the soil arsenic pollution is considered as a serious environmental issue, and the high toxicity of arsenic can seriously affect the quality and safety of agricultural products and human health. Biochar, as a solidifying/passivating agent, has been widely used in the treatment of soil heavy metal pollution. Pine biochar (BC) was used as a carrier in this study, and biochar-loaded nano-zirconia (N-ZrO-BC) was synthesized to investigate its adsorption and fixation characteristics on As (V) in soil and water.

hsa_circ_001946 elevates HOXA10 expression and promotes the development of endometrial receptivity via sponging miR-135b.

Background: Impaired endometrial receptivity is a major reason for embryo implantation failure. There's a paucity of information regarding the role of circRNAs on endometrial receptivity. Here, we investigated the function of hsa_circ_001946 on endometrial receptivity and its mechanisms.

Association Between Body Mass Index and Male Sperm Apoptosis and Apoptosis-Related Factors.

Background: Although obesity may affect reproductive functions, the molecular mechanisms of apoptosis-related biomarkers remain uncertain.

Objective: To examine the effects of body mass index on sperm quality and apoptosis-related factors in seminal plasma of men.

Methods: Data for 54 subfertile men were collected at our reproductive medical center.

Research on Creeping Flashover Characteristics of Nanofluid-Impregnated Pressboard Modified Based on Fe₃O₄ Nanoparticles under Lightning Impulse Voltages.

Creeping flashover of mineral-oil-impregnated pressboard under impulse stress is a common insulating failure in oil-immersed transformers, arousing increasing attention. Recent studies have shown that the breakdown strength of transformer oil under positive lightning impulse voltage can be significantly improved through nanoparticles-based modification, and Fe₃O₄ has shown the best improvement in breakdown strength compared to other nanoparticles that have been used. This paper presents the creeping flashover characteristics of pure oil-impregnated pressboard (OIP) and nanofluid-impregnated pressboard (NIP) based on Fe₃O₄ nanoparticles under positive and negative lightning impulse voltages, respectively.

Polarization and Trap Characteristics Modification of Oil-Impregnated Paper Insulation by TiO₂ Nanoparticles.

Polarization and traps determine the electrical property of oil-paper insulation, but most attention has been paid to the modification of insulating oil with nanoparticles, so there are is little research about oil-impregnated paper, and the origin for performance variation is not understood yet. In this paper, spherical nanoscale titanium dioxide was prepared by the hydrolysis method and nanofluid-impregnated paper (NP) was fabricated through oil-impregnation. The frequency domain spectrum was measured for polarization analysis, and both thermally stimulated depolarization current (TSDC) and isothermal surface potential decay (ISPD) methods were used to reveal trap parameters.

Effect of Nanoparticle Morphology on Pre-Breakdown and Breakdown Properties of Insulating Oil-Based Nanofluids.

Nanoparticles currently in use are challenged in further improving the dielectric strength of insulating oil. There is a great need for a new type of nanoparticle to promote the application of insulating oil-based nanofluids in electric industries. This paper experimentally investigates the effect of nanoparticle morphology on pre-breakdown and breakdown properties of insulating oil-based nanofluids.

Effect of Dispersion Method on Stability and Dielectric Strength of Transformer Oil-Based TiO Nanofluids.

Dispersion stability of nanoparticles in the liquid media is of great importance to the utilization in practice. This study aims to investigate the effects of mechanical dispersion method on the dispersibility of functionalized TiO nanoparticles in the transformer oil. Dispersion methods, including stirring, ultrasonic bath, and probe processes, were systematically tested to verify their versatility for preparing stable nanofluid.

Seed-mediated synthesis and characterization of Ni flower-like nanomaterials.

Flower-like Ni nanoparticles in diameter of 200 approximately 250 nm were synthesized by a mild chemical solution method. They were composed of smaller single-crystal Ni grains with an average diameter of approximately 15 nm. XRD, EDS and HRTEM results show that these particles were mixed uniformly with iron oxide single crystals, which serve as seeds for the growth of the flower-like structure.