Publications by authors named "Yuzhan Chen"
Background: Chronic lymphocytic leukemia (CLL) is a common hematologic malignancy. Although previous research has explored associations between plasma proteins and CLL, the causal relationships remain unclear. This study used Mendelian randomization (MR) to investigate the causal relationship between 7156 plasma proteins and CLL risk.
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- Indolent lymphomas often experience histological transformation (HT), which can worsen prognosis and complicate treatment.
- A case of splenic marginal zone lymphoma (SMZL) with an MYD88 mutation transformed into diffuse large B-cell lymphoma (DLBCL), revealing new genetic abnormalities.
- The significance of the MYD88 gene in SMZL remains uncertain, highlighting the need for more research on similar cases to better understand its role.