Int J Biol Macromol
December 2024
Lipid droplets (LDs) are organelles specialized in the storage of neutral lipids, cholesterol esters and triglycerides, thereby protecting cells from the toxicity of excess lipids while allowing for the mobilization of lipids in times of nutrient deprivation. Defects in LD function are associated with many diseases. S-acylation mediated by zDHHC acyltransferases modifies thousands of proteins, yet the physiological impact of this post-translational modification on individual proteins is poorly understood.
View Article and Find Full Text PDFUnlabelled: Members of , although typically opportunistic, can cause severe infections in immunocompromised hosts. Recent advances in genome sequencing provide an opportunity for more precise study of this genus. In this study, we first identified and characterized a novel species named sp.
View Article and Find Full Text PDFis a clinically significant opportunistic pathogen that is involved in urinary tract infections. Due to the resolution limitations of identification, distinguishing from closely related species is challenging by commercial biochemical test systems. Here, we first reported a novel species, , which had been misidentified as .
View Article and Find Full Text PDF(Fabaceae), a nitrogen-fixing tree species, is critically important for coastal protection in southeast China. In this study, we report the complete chloroplast genome sequence of , with a length of 176,493 bp. It contains a pair of inverted repeats (IR 39,851 bp), a large single-copy region (LSC 91,869 bp), and a small single-copy region (SSC 4,922 bp).
View Article and Find Full Text PDFThe nucleotide oligomerization domain (NOD)-like receptors 1 and 2 (NOD1/2) are intracellular pattern-recognition proteins that activate immune signaling pathways in response to peptidoglycans associated with microorganisms. Recruitment to bacteria-containing endosomes and other intracellular membranes is required for NOD1/2 signaling, and NOD1/2 mutations that disrupt membrane localization are associated with inflammatory bowel disease and other inflammatory conditions. However, little is known about this recruitment process.
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