Publications by authors named "Yuyue Xie"
LysR-type transcriptional regulators (LTTRs) are ubiquitously distributed and abundant transcriptional regulators in prokaryotes, playing pivotal roles in diverse physiological processes. Nonetheless, despite their prevalence, the intricate functionalities and physiological implications of this protein family remain incompletely elucidated. In this study, we employed a comprehensive approach to deepen our understanding of LTTRs by generating a collection of 20 LTTR gene-deletion strains in Aeromonas hydrophila, accounting for 42.
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- Aeromonas hydrophila is a major pathogen in aquaculture, with drug-resistant strains complicating treatment efforts and antibiotic use promoting further resistance.
- A study utilized quantitative proteomics to compare protein expression in A. hydrophila under streptomycin stress versus normal conditions, revealing key insights into its resistance mechanisms.
- Bioinformatics tools identified important metal-binding pathways and specific gene deletions that contribute to A. hydrophila's adaptation to streptomycin, enhancing our understanding of its resistance strategies.