Publications by authors named "Yuyuan Luo"
Article Synopsis
- Low concentrations of gelatin (0.02-0.20 wt%) were used to alter the surface properties of cellulose nanocrystals (CNC) by creating CNC/gelatin complexes, resulting in changes in potential values from -44.50 to -17.93 mV as gelatin concentration increased.
- Different gelatin concentrations affected the micromorphology of the CNC/g gelatin complexes, causing interconnection of particles at 0.10 wt% and leading to a more aggregated network structure at higher concentrations.
- When gelatin concentration exceeded 0.10%, stable high internal phase emulsions (HIPE) could be formed, with stabilization mechanisms varying based on concentration: lower concentrations relied on interface adsorption and network structure, while higher
This study fabricated nanocellulose lightweight porous material (TOCNF-G-LPM-TA) as absorbent fresh-keeping pad for meat products, using TEMPO-oxidized cellulose nanofibril (TOCNF) and gelatin as structural skeleton and tannic acid (TA) as antibacterial component of TOCNF lightweight porous material (TOCNF-G-LPM). The adsorption kinetics, capacity and mechanism of TOCNF-G-LPM in different initial concentrations of TA solutions were investigated, the antioxidant and antibacterial properties of TOCNF-G-LPM-TA and its fresh-keeping effect on refrigerated pork at 4 ℃ were studied. Due to strong hydrogen bonding and porous structure, TOCNF-G-LPM exhibited excellent TA adsorption ability (230 mg/g) conforming with pseudo-second-order kinetic and Langmuir isotherm models.
View Article and Find Full Text PDFArticle Synopsis
- The study focuses on creating a lightweight porous material (TOCNF-G-LPM) using TEMPO-oxidized cellulose nanofibril and gelatin, with glutaraldehyde as a crosslinking agent.
- Increasing the gelatin concentration enhanced the material's porosity (from 98.53% to 97.40%) and decreased its density (from 0.0372 to 0.0236 g/cm³), while also leading to a more organized internal structure.
- Gelatin addition improved the thermal and mechanical properties of the material, reduced its water and oil absorption, and showed good biocompatibility with no negative effects on the growth of the model organism C. elegans.
The physical and chemical properties of cellulose nanocrystals (CNC) were regulated by physical crosslinking with chitosan particles (CSp). At a fixed concentration (0.5 wt%) of CNC, varying CSp concentration (0.
View Article and Find Full Text PDFLiver fibrosis has the potential to progress into liver cirrhosis, liver failure, and even death. Hepatic stellate cells (HSCs) activation play a central role in liver fibrosis, and persistently damaged hepatocytes secrete soluble factors that activate transdifferentiation of HSCs into myofibroblasts. Our previous studies indicated that fine particulate matter (PM2.
View Article and Find Full Text PDFPM2.5-exposed hepatocytes induce hepatic stellate cells activation by releasing TGF-β1.
Biochem Biophys Res Commun
September 2021
The interaction between various types of hepatic cells is related to liver fibrosis. Recent studies demonstrated that fine particulate matter (PM2.5) exposure is an important risk factor for the occurrence of liver fibrosis, but its molecular mechanism is still obscure.
View Article and Find Full Text PDFBackground: To evaluate the association between the genetic polymorphism of the solute carrier organic anion transporter family member 1B1 (SLCO1B1, also known as organic anion transport polypeptide C) and hyperbilirubinemia in Chinese neonates.
Methods: 183 infants with hyperbilirubinemia and 192 control subjects from the Fifth People's Hospital of Shenzhen were recruited. Polymerase chain reaction, restriction fragment length polymorphisms and agarose gel electrophoresis techniques were used to detect genetic variants of SLCO1B1.
Objective: To determine whether three variants (388 G>A, 521 T>C, and 463 C>A) of the solute carrier organic anion transporter family member 1B1 (SLCO1B1) are associated with neonatal hyperbilirubinemia.
Data Source: The China National Knowledge Infrastructure and MEDLINE databases were searched. The systematic review with meta-analysis included genetic studies which assessed the association between neonatal hyperbilirubinemia and 388 G>A, 521 T>C, and 463 C>A variants of SLCO1B1 between January of 1980 and December of 2012.
Background: Recent reports have suggested that genetic factors, including mutations in the coding region or promoter of uridine diphosphate-glucuronosyltransferase 1A1 (UGT1A1) may increase the risk of development of neonatal hyperbilirubinemia, but the relationship has not been evaluated on systematic review or meta-analysis.
Methods: A meta-analysis of observational studies reporting effect estimates and 95% confidence intervals (95%CI) was conducted on the association between UGT1A1 polymorphisms and neonatal hyperbilirubinemia.
Results: A total of 27 eligible studies were identified.
Aim: To determine whether the UDP-glucuronosyltransferase 1A1 gene (UGT1A1) Gly71Arg (211G>A) mutation is associated with neonatal hyperbilirubinemia.
Methods: The study consisted of two parts. The case-control study included 112 hyperbilirubinemic infants and 105 control subjects from the Fifth People's Hospital of Shenzhen.