Publications by authors named "Yuyu Zhong"

Breast cancer has become one of the top five commonest causes of cancer death. The use of ferroptosis to induce the generation of reactive oxygen species (ROS) in cancer cells presents a promising and potential strategy for cancer treatment. Herein, a series of facile bimetallic nanoparticles (% Fe-doped ZIF-8) were synthesized and tested, and doxorubicin (DOX), a classic drug for breast cancer therapy, was encapsulated.

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Introduction: Metal-organic frameworks (MOFs) are one of the typical coordination polymers which constructed by metal ions/clusters and multitopic organic ligands. Compared with traditional porous materials, MOFs have the advantages of significant porosity, large specific surface area, adjustable chemical composition, and structure tailorability, these unique features make them a promising candidate for controlled drug delivery.

Areas Covered: This review aims to summarize recent advances in the development of MOFs for drug delivery, in particular, focusing on its ability to deliver various drugs and their release mechanism, as well as the and biological evaluation.

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Many effluents contain various antibiotics commonly, where the simultaneous removal of them is a big challenge. In this study, the magnetic biocomposite (eggshell-zeolitic imidazolate framework) was designed and synthesized by green and facile method. Zeolitic imidazolate framework-8 (ZIF-8) particles were stabilized on the surface of magnetic eggshell (FeO-ES), generating a new FeO-ES/ZIF-8 adsorbent, which was also fully characterized using FTIR, XRD, SEM and BET techniques.

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Background: To date, number of new and attractive materials have been applied in drug delivery systems (DDDs) to improve the efficiency of the treatment of cancers. Some problems like low stability, toxicity and weak ability of targeting have hampered most of materials for further applications in biomedicine. MIL(MIL = Materials of Institute Lavoisier), as a specific subclass of metal-organic frameworks (MOFs) owns more advantages than other subclass MOFs, such as better biodegradability and lower cytotoxicity.

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Still today, cancer remains a threat to human health. Possible common treatments to cure this disease include chemotherapy (CT), radiotherapy (RT), photothermal therapy (PTT), and surgical resection, which give unreasonable results because of their limited efficiency and also lead to side-effects. Hence, different strategies are now being exploited to not only enhance the efficiency of these traditional therapeutic methods or treat the tumor cells but also curtail the side effects.

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Two new metal-organic coordination polymers (CPs), aqua-2,2'-bipyridine-5-(4'-carboxylphenoxy)isophthalatezinc(ii) polymer [Zn(HL)(2,2'-bipy)(HO)] (1) and tris-4,4'-bipyridine-bis-5-(4'-carboxylphenoxy)isophthalatetrizinc(ii) polymer [Zn(L)2(4,4'-bipy)] (2) (HL = 5-(4'-carboxylphenoxy)isophthalic acid, 4,4'-bipy = 4,4'-bipyridine and 2,2'-bipy = 2,2'-bipyridine), were obtained under hydrothermal conditions and characterized by microanalysis, FTIR spectroscopy and single crystal X-ray diffraction. The single crystal X-ray diffraction indicated that in both the CPs the coordination networks exhibited varied topologies and coordination modes around the Zn(ii) centers. CP 1 exhibits a one-dimensional (1D) chain structure, which further forms a 3D supramolecular architecture intermolecular π⋯π and hydrogen bonding interactions, while 2 possesses a 3D framework generated from a 2D layered motif comprising zinc and tripodal carboxylate subunits pillared by 4,4'-bpy ligands.

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Although dyslipidemia is associated with cardiovascular disease, there are conflicting data about the role of serum lipids and their ratios in promoting arterial stiffness. The authors aimed to compare serum lipid profiles to predict arterial stiffness, which was assessed by brachial-ankle pulse wave velocity in young Chinese men. A total of 1015 participants aged 18 to 44 years without serious comorbidities were recruited for conventional detection.

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Objectives: High triglycerides and low high density lipoprotein cholesterol are important cardiovascular risk factors. Triglyceride to high-density lipoprotein cholesterol ratio (TG/HDL-C) has been reported to be useful in predicting cardiovascular disease. Brachial-ankle pulse wave velocity (baPWV) is a valid and reproducible measurement by which to assess arterial stiffness and a surrogate marker of atherosclerosis.

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