Publications by authors named "Yuying Shi"

Bacillus thuringiensis (Bt) is affected by ultraviolet radiation and bacterial sedimentation in pest control applications, leading to low pesticide utilization and a short duration of control. To improve Bt stability in these applications and prolong the duration of biological control, Bt LLP29 was first encapsulated using double emulsion technology, resulting in the formation of W/O/W double emulsion microcapsules with sodium lignosulfonate and chitosan as wall materials. The morphological structure and functionality of microcapsules were then systematically investigated.

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Chlortetracycline (CTE) is a kind of tetracycline antibiotic against Gram-positive and negative bacteria. However, the overuse and excessive discharge of CTE would be harmful to the environment and human beings inevitably. Herein, to achieve sensitive and specific detection of CTE, an electron-deficient site (i.

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Correction for 'Self-generating electricity system driven by aqueous humor flow and trabecular meshwork contraction motion activated BKCa for glaucoma intraocular pressure treatment' by Ruiqi Wang , , 2025, https://doi.org/10.1039/D4MH01004C.

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The repair of nerve damage has long posed a challenge owing to limited self-repair capacity and the highly differentiated nature of nerves. While new therapeutic and pharmacologic interventions have emerged in neurology, their regenerative efficacy remains limited. Tissue engineering offers a promising avenue for overcoming the limitations of conventional treatments and increasing the outcomes of regenerative repair.

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This case report presents an incident of spontaneous migration of a peripherally inserted central catheter (PICC) into the azygos vein, leading to accidental transection during surgery. A patient with esophageal cancer had a PICC placed in the left upper arm one day prior to surgery, with the catheter tip confirmed by intracavitary electrocardiogram (IC-ECG) and anterior/lateral chest X-ray imaging. However, during the surgery, the PICC was unintentionally cut when the surgeon isolated and clamped the azygos vein.

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Primary open-angle glaucoma (POAG) is the most common form of glaucoma and the leading cause of irreversible vision loss and blindness worldwide. Intraocular pressure (IOP) is the only modifiable risk factor, and prompt treatment to lower IOP can effectively slow the rate of vision loss due to glaucoma. Trabecular meshwork (TM) cells can maintain IOP homeostasis by correcting and adjusting the resistance to aqueous humor outflow in response to sustained pressure changes.

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Motivation: Enzymatic reaction play a pivotal role in regulating cellular processes with a high degree of specificity to biological functions. When enzymatic reactions are disrupted by gene, protein, or metabolite dysfunctions in diseases, it becomes crucial to visualize the resulting perturbed enzymatic reaction-induced multi-omics network. Multi-omics network visualization aids in gaining a comprehensive understanding of the functionality and regulatory mechanisms within biological systems.

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Article Synopsis
  • Researchers came up with a new method using special molecules called cell-penetrating peptide-induced chimera conjugates (cp-PCCs) to target a protein called DHHC3, which helps keep another protein, PD-L1, stable on cancer cells.
  • By breaking down DHHC3, this method can reduce PD-L1 levels, making it easier for the immune system to fight tumors.
  • In tests with mice, one specific cp-PCC called PCC16 was very effective at lowering PD-L1 and helped fight tumors without causing many side effects, showing promise for cancer treatment.
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Gastric adenocarcinoma is one of the most death cause cancers worldwide. Metabolomics is an effective approach for investigating the occurrence and progression of cancer and detecting prognostic biomarkers by studying the profiles of small bioactive molecules. To fully decipher the functional roles of the disrupted metabolites that modulate the cellular mechanism of gastric cancer, integrated gene-metabolite association network methods are critical to map the associations between metabolites and genes.

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  • Studies on mitochondrial genome evolution show varying results, particularly in flatworms, which have the fastest-evolving mitogenomic sequences among bilaterians.
  • Researchers analyzed 223 flatworm species using phylogenetic models, finding that factors like thermic host environment and longevity had minimal effect on sequence evolution and genome size.
  • The study highlights that parasitism significantly explains branch length variability in flatworms, with free-living turbellaria evolving more quickly than parasitic Neodermata, suggesting the need to consider lineage-specific factors and the episodic nature of evolutionary changes in these analyses.
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Libraries of collision cross-section (CCS) values have the potential to facilitate compound identification in metabolomics. Although computational methods provide an opportunity to increase library size rapidly, accurate prediction of CCS values remains challenging due to the structural diversity of small molecules. Here, we developed a machine learning (ML) model that integrates graph attention networks and multimodal molecular representations to predict CCS values on the basis of chemical class.

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Visual information is important for accurate spatial coding and memory-guided navigation. As a crucial area for spatial cognition, the medial entorhinal cortex (MEC) harbors diverse spatially tuned cells and functions as the major gateway relaying sensory inputs to the hippocampus containing place cells. However, how visual information enters the MEC has not been fully understood.

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Developing lightweight composite with reversible switching between microwave (MW) absorption and electromagnetic interference (EMI) shielding is promising yet remains highly challenging due to the completely inconsistent attenuation mechanism for electromagnetic (EM) radiation. Here, a lightweight vanadium dioxide/expanded polymer microsphere composites foam (VO/EPM) is designed and fabricated with porous structures and 3D VO interconnection, which possesses reversible switching function between MW absorption and EMI shielding under thermal stimulation. The VO/EPM exhibits MW absorption with a broad effective absorption bandwidth of 3.

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Multiple patch-clamp recordings and morphological reconstruction are powerful approaches for neuronal microcircuitry dissection and cell type classification but are challenging due to the sophisticated expertise needed. Here, we present a protocol for applying these techniques to neurons in the medial entorhinal cortex (MEC) of mice. We detail steps to prepare brain slices containing MEC and perform simultaneous multiple whole-cell recordings, followed by procedures of histological staining and neuronal reconstruction.

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Article Synopsis
  • * This new Ag-CNT film shows significantly improved electrical conductivity, reaching 6.82 × 10 S/m, and excellent EMI shielding effectiveness, exceeding 66 dB across a wide frequency range (3-40 GHz).
  • * Additionally, the mechanical properties of the Ag-CNT film are greatly enhanced, with tensile strength and Young's modulus increasing by approximately 253% and 795%, respectively, making it suitable for future portable and wearable electronic devices.
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  • The study aimed to explore the factors influencing anal fistula and anorectal abscess, which have not been thoroughly researched before.
  • Researchers conducted a retrospective analysis of 1,223 patients visiting a proctology department, focusing on how body mass index (BMI) affected the risk of these conditions.
  • The results showed that overweight and obese individuals were at a significantly higher risk for both anal fistulas and anorectal abscesses, suggesting a J-shaped relationship between increasing BMI and the likelihood of developing these issues.
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  • Polyphenols are natural compounds known for their antioxidant and anti-inflammatory properties, making them valuable in medicine for applications like drug delivery and tissue engineering.
  • * They enhance biomaterials' performance by improving drug stability and release kinetics, leading to better therapeutic outcomes and targeted delivery.
  • * In tissue engineering, polyphenols support cell adhesion and growth, aiding in the development of functional tissues while providing biocompatibility and mechanical strength for scaffolds.
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Background: As a special type of wetland, the new wetland in the coal mining subsidence area is highly sensitive to environmental changes. In recent years, more and more attention has been paid to the studies of soil microbial diversity in newly born wetlands in coal mining subsidence areas. However, there are few reports on the seasonal variation of soil microbial diversity and its relationship with soil physical and chemical properties.

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A formal [4 + 2]-cycloaddition reaction of -alkoxy acrylamides and acyl isothiocyanates was developed a Lewis base-catalyzed cascade aza-nucleophilic addition/thio-Michael addition process under mild conditions. This study provides a facile approach for preparing 2-imino-1,3-thiazinone derivatives in moderate to excellent yields and enriches the field of heterocyclic acrylamide chemistry. The reported method features metal-free reaction conditions, high atom economy, and easy operation.

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Introduction: Our previous research has found that degradation of palmitoyltransferase in tumor cells using a linear peptide PROTAC leads to a significant decrease in PD-L1 expression in tumors. However, this degradation is not a sustained and efficient process. Therefore, we designed a cyclic peptide PROTAC to achieve this efficient anti-PD-L1 effect.

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Metal-organic frameworks (MOFs) are often used as carriers in the preparation of electrochemiluminescent (ECL) materials, and ECL materials stabilized in the aqueous phase can be prepared by encapsulating chromophores inside MOFs by an in situ growth method. In this study, nanocomposites MIL-88B(Fe)-NH@Ru(py) with excellent ECL response were prepared by encapsulating Tris(2,2'-bipyridine)ruthenium dichloride (Ru(py)) inside MIL-88B(Fe)-NH using the one-step hydrothermal method. MIL-88B(Fe)-NH possesses abundant amino groups, which can accelerate the catalytic activation process of KSO, and its abundant pores are also conducive to the enhancement of the transmission rate of co-reactant agents, ions, and electrons, which effectively improves the ECL efficiency.

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Introduction: The soil bacteria promote the circulation conversion of lake nutrients and play an important role in maintaining the balance of the lake ecosystem. Few studies have investigated the association of seasonal variation in bacteria and environmental factors in inland freshwater lake wetlands. Nansi Lake is a large shallow freshwater lake in northern China.

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Article Synopsis
  • This study investigates Layer 1 interneurons (L1INs) in the medial entorhinal cortex (MEC) to understand their role in brain function, as their microcircuitry is not well understood.
  • Researchers identified three distinct types of L1INs, each with unique morphological and electrical characteristics, and discovered different connectivity patterns compared to the neocortex.
  • The study also highlights a dorsoventral gradient in L1IN microcircuits, where specific cells show varied input and inhibitory effects on principal neurons, helping to clarify the function of L1INs in the MEC.
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Background: Anal fistula is an anorectal infectious disease caused by a perianal abscess or perianal disease. Accurate anorectal examinations are of great significance. The two-finger digital rectal examination (TF-DRE) has been used in clinical practice, with a lack of comprehensive research on the value of the TF-DRE in the diagnosis of anal fistula.

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