Cationized Decalcified Bone Matrix for Infected Bone Defect Treatment.

We aim to develop a dual-functional bone regeneration scaffold (Q-D) with antibacterial and osteogenic properties for infected bone defect treatment. This study provides insights into antibacterial components that could be combined with naturally derived materials through a facile Schiff base reaction, offering a potential strategy to enhance antibacterial properties. Naturally derived decalcified bone matrix (DBM) has been reported to be porous and biodegradable.