Career aspiration and influencing factors study of intern nursing students: A latent profile analysis.

Background: The intensifying global aging population exacerbates the serious shortage of nurses, placing immense pressure on the healthcare system worldwide. Overwhelming workloads, limited career development opportunities, and high turnover rates among nurses compound these challenges. Career aspiration is closely related to individual active work behavior and career orientation, and is significant for stabilizing the nursing team.

Influence of nurses' narrative competence on communication ability with angry patients: The mediating effect of reflection.

Aim: To examine if reflection mediates the relationship between narrative competence and nurses' communication ability with angry patients.

Background: Workplace violence is a significant hazard in clinical settings and leads to deleterious effects on health workers. Anger is a key contributing factor to aggressive behavior, and effectively managing patients' anger can help mitigate the risk of workplace violence.

Health prediction for king salmon via evolutionary machine learning with genetic programming.

King (Chinook) salmon is the only salmon species farmed in Aotearoa New Zealand and accounts for over half of the world's production of king salmon. Determining the health status of king salmon effectively is important for farming. However, it is a challenging task due to the complex biotic and abiotic factors that influence health.

Percutaneous Kyphoplasty Alleviates Pain Occurring Distal to the Fracture Area Caused by Stage I and II Kümmell Disease.

Background: Kümmell disease (KD)-a rare and relatively complex spinal condition-is a type of posttraumatic osteoporotic vertebral compression fracture manifesting as a delayed collapse of a vertebral body. Although most patients with KD present with pain in the fracture area, some present with pain in the rib region or distal lumbosacral region, without pain in the fracture area, which poses challenges for diagnosing and treating KD.

Objective: We aimed to explore whether percutaneous kyphoplasty can alleviate pain distal to the fracture area caused by either Stage I or Stage II KD.

Seven undescribed compounds from dried flower buds of Ochrocarpus longifolius.

Seven unreported compounds were isolated from dried flower buds of Ochrocarpus longifolius in this study, including an alkaloid ochrocaracid A (1), five coumarins ochrocarpins I (2), J (3), K (4), L (5), and M (6), and one styryl-2-pyranone compound iresinoacid (7) and nine known compounds (8-16). All these compounds were found in O. longifolius for the first time.

The paths of career aspiration for intern nursing students: A fuzzy-set qualitative comparative analysis.

Aim: This study was conducted to explore the combination of different conditional variables that led to high career aspiration of intern nursing students.

Background: A severe shortage of nurses exists nationwide, and nurses' low career aspiration contribute to high turnover rates and hinder the high-quality development of the nursing field. Nursing students undergoing clinical practice will become the backbone of future nursing staff.

The need for thoracic magnetic resonance imaging before vertebral augmentation surgery in patients with lumbar vertebral fractures.

Background: Osteoporotic vertebral compression fractures (OVCFs) of the lumbar region may be accompanied by thoracic fractures. Treating only the lumbar fractures can lead to worsening of the thoracic fractures or unresolved postoperative symptoms. This study aims to investigate the need to perform thoracic MRI before vertebral augmentation (including percutaneous vertebroplasty and percutaneous kyphoplasty) in patients with lumbar OVCF.

Programmable Entropy-Driven Circuit-Cascaded Self-Feedback DNAzyme Network for Ultra-Sensitive Fluorescence and Photoelectrochemical Dual-Mode Biosensing.

Inspired by natural DNA networks, programmable artificial DNA networks have become an attractive tool for developing high-performance biosensors. However, there is still a lot of room for expansion in terms of sensitivity, atom economy, and result self-validation for current microRNA sensors. In this protocol, miRNA-122 as a target model, an ultrasensitive fluorescence (FL) and photoelectrochemical (PEC) dual-mode biosensing platform is developed using a programmable entropy-driven circuit (EDC) cascaded self-feedback DNAzyme network.

Fast and Robust Infrared Small Target Detection Using Weighted Local Difference Variance Measure.

Infrared (IR) small-target-detection performance restricts the development of infrared search and track (IRST) systems. Existing detection methods easily lead to missed detection and false alarms under complex backgrounds and interference, and only focus on the target position while ignoring the target shape features, which cannot further identify the category of IR targets. To address these issues and guarantee a certain runtime, a weighted local difference variance measure (WLDVM) algorithm is proposed.

Percutaneous Kyphoplasty to Relieve the Rib Region Pain in Osteoporotic Thoracic Vertebral Fracture Patients Without Local Pain of Fractured Vertebra.

Background: Osteoporotic vertebral compression fractures (OVCF) are common. A few patients with thoracic vertebral fracture show pain in the bilateral rib region but not at the fracture site. The point of specific tenderness in the rib region cannot be located.

Multi-Scale Strengthened Directional Difference Algorithm Based on the Human Vision System.

The human visual system (HVS) mechanism has been successfully introduced into the field of infrared small target detection. However, most of the current detection algorithms based on the mechanism of the human visual system ignore the continuous direction information and are easily disturbed by highlight noise and object edges. In this paper, a multi-scale strengthened directional difference (MSDD) algorithm is proposed.

The evaluation of next-generation sequencing assisted pathogenic detection in immunocompromised hosts with pulmonary infection: A retrospective study.

Introduction: Pulmonary infections are frequent in immunocompromised hosts (ICH), and microbial detection is difficult. As a new method, next-generation sequencing (NGS) may offer a solution.

Objectives: This study aimed to assess the impact of NGS-assisted pathogenic detection on the diagnosis, treatment, and outcomes of ICH complicated by pulmonary infection and radiographic evidence of bilateral diffuse lesions.

Local Anesthetic and Steroid Injection to Relieve the Distal Lumbosacral Pain in Osteoporotic Vertebral Compression Fractures of Patients Treated with Kyphoplasty.

Background: Percutaneous kyphoplasty (PKP) is widely used in osteoporotic vertebral compression fractures (OVCF). But in some patients, distal lumbosacral pain (DLP) persists even after treatment and affects their quality of life.

Objective: To investigate the effectiveness of local anesthetic and steroid injection in improving DLP after PKP.

Government Information Dissemination During Public Health Emergencies: An Analysis of China's Experiences.

Information disclosure is crucial in China's official response to the COVID-19 pandemic. Since the early phase of the pandemic, the government's method of communication has relied heavily upon its analysis of information disclosed during past public health emergencies. This approach was proposed to better inform and prepare citizens during the crisis.

Effect of High Rotational-Speed Friction-Stir Welding on Microstructure and Properties of Welded Joints of 6061-T6 Al Alloy Ultrathin Plate.

The butt joint of an Al alloy ultrathin plate with a thickness of 0.5 mm is realized by a high rotational-speed friction-stir welding process. It overcomes the welding difficulty that the ultrathin plate is often torn, and it cannot be formed by conventional friction-stir welding.

Adipose/Connective Tissue From Thyroid-Associated Ophthalmopathy Uncovers Interdependence Between Methylation and Disease Pathogenesis: A Genome-Wide Methylation Analysis.

In response to pathological stimulation, methylation status conversion of the genome drives changes of cell feature and is able to promote disease development. Yet the role of methylation in the development of thyroid-associated ophthalmopathy (TAO) remains to be evaluated. Overexpansion of orbital tissue is the key feature of TAO.

Sleep Deprivation Disturbs Immune Surveillance and Promotes the Progression of Hepatocellular Carcinoma.

Sleep disturbance is common in patients with cancer and is associated with poor prognosis. However, the effects of sleep deprivation (SD) on immune surveillance during the development of hepatocellular carcinoma (HC) and the underlying mechanisms are not known. This was investigated in the present study using mouse models of SD and tumorigenesis.

Programmable DNA Circuits for Flexible and Robust Exciton-Plasmon Interaction-Based Photoelectrochemical Biosensing.

DNA circuits as one of the dynamic nanostructures can be rationally designed and show amazing geometrical complexity and nanoscale accuracy, which are becoming increasingly attractive for DNA entropy-driven amplifier design. Herein, a novel and elegant exciton-plasmon interaction (EPI)-based photoelectrochemical (PEC) biosensor was developed with the assistance of a programmable entropy-driven DNA amplifier and superparamagnetic nanostructures. Low-abundance miRNA-let-7a as a model can efficiently initiate the operation of the entropy-driven DNA amplifier, and the released output DNAs can open the partially hybridized double-stranded DNA anchored on FeO@SiO particles.

Microbial responses underlying the denitrification kinetic shifting exposed to ng/L- and μg/L-level lomefloxacin in groundwater.

The emerging co-contaminant of antibiotics and nitrate has acquired great concerns worldwide, which poses a potential impact on denitrification in the ecological environment, but little is known about the groundwater system at lower antibiotic concentration, especially ng/L-level. Herein the frequently detected Lomefloxacin (LOM) in groundwater was selected to explore its influences on denitrification kinetics and microbial dynamic responses. The NO-N removals in ng/L-μg/L LOM-amended reactors (8.

DNA-Tetrahedral-Nanostructure-Based Entropy-Driven Amplifier for High-Performance Photoelectrochemical Biosensing.

In virtue of the inherent molecular recognition and programmability, DNA has recently become the most promising for high-performance biosensors. The rationally engineered nucleic acid architecture will be very advantageous to hybridization efficiency, specificity, and sensitivity. Herein, a robust and split-mode photoelectrochemical (PEC) biosensor for miRNA-196a was developed based on an entropy-driven tetrahedral DNA (EDTD) amplifier coupled with superparamagnetic nanostructures.

Magnetic-Assisted Methylene Blue-Intercalated Amplified dsDNA for Polarity-Switching-Mode Photoelectrochemical Aptasensing.

Organic dyes are typically applied as photosensitizers in photoelectrochemical (PEC) cells but have not been reported in polarity-reversal-mode PEC sensors with excellent sensitivity and accuracy. Herein, an elegant and robust PEC biosensor for carcinoembryonic antigen (CEA) has been designed by photocurrent polarity switching of CdTe quantum dots (QDs), which is obtained by embedding methylene blue (MB) into amplified double-stranded DNA (dsDNA) anchored to the superparamagnetic FeO@SiO. The target-triggered Exo III-assisted cyclic amplification strategy and in situ magnetic enrichment enable the remarkable sensitivity.

Coagulopathy is a major extrapulmonary risk factor for mortality in hospitalized patients with COVID-19 with type 2 diabetes.

Introduction: To investigate the risk factors for the death in patients with COVID-19 with type 2 diabetes mellitus (T2DM).

Research Design And Methods: We retrospectively enrolled inpatients with COVID-19 from Wuhan Jinyintan Hospital (Wuhan, China) between December 25, 2019, and March 3, 2020. The epidemiological and clinical data were compared between non-T2DM and T2DM or between survivors and non-survivors.

Corticosteroid therapy for coronavirus disease 2019-related acute respiratory distress syndrome: a cohort study with propensity score analysis.

Background: The impact of corticosteroid therapy on outcomes of patients with coronavirus disease 2019 (COVID-19) is highly controversial. We aimed to compare the risk of death between COVID-19-related ARDS patients with corticosteroid treatment and those without.

Methods: In this single-center retrospective observational study, patients with ARDS caused by COVID-19 between January 20, 2020, and February 24, 2020, were enrolled.

[Statistics and Analysis of 136 Cases of Adverse Events of International Medical Devices].

To explore the law and characteristics of adverse events of medical devices and to provide research methods and basis for reducing the recurrence of similar adverse events, we collect medical devices safety information from five representative countries in the world, and make statistics and analysis on the types of events, the types of management and the causes of events. The results show that among 136 serious adverse events, the top three causes of recall are product design factors, software factors, and component defects. In order to reduce the application risk of medical devices, it is suggested that product designers, operating users and medical institutions should correctly implement the monitoring and evaluation system of medical devices.

Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China.

Importance: Coronavirus disease 2019 (COVID-19) is an emerging infectious disease that was first reported in Wuhan, China, and has subsequently spread worldwide. Risk factors for the clinical outcomes of COVID-19 pneumonia have not yet been well delineated.

Objective: To describe the clinical characteristics and outcomes in patients with COVID-19 pneumonia who developed acute respiratory distress syndrome (ARDS) or died.