Publications by authors named "Yuya Murakami"

Background: Grey-white matter ratio (GWR) measured by head computed tomography (CT) scan is known as a neurological prognostication tool for out-of-hospital cardiac arrest (OHCA) survivors. The prognostic value of GWR obtained early (within two hours after return of spontaneous circulation [ROSC]) remains a matter of debate.

Methods: We conducted a multicenter, retrospective, observational study at five hospitals.

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Objective: This study investigates temporal muscle atrophy in out-of-hospital cardiac arrest patients post-resuscitation, seeking associations with neurological outcomes and factors associated with atrophy.

Methods: Using data from six Japanese intensive care units, adult patients' post-resuscitation who underwent head computed tomography scans on admission and two to five days post-admission were assessed. Temporal muscle area, thickness, and density were quantified from a single cross-sectional image.

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Background: Sudden loss of consciousness as a result of cardiac arrest can cause severe traumatic head injury. Collapse-related traumatic intracranial hemorrhage (CRTIH) following out-of-hospital cardiac arrest (OHCA) may be linked to poor neurological outcomes; however, there is a paucity of data on this entity. This study aimed to investigate the frequency, characteristics, and outcomes of CRTIH following OHCA.

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The Hansen solubility parameter (HSP) is a useful index for reasoning the gelation behavior of low-molecular-weight gelators (LMWGs). However, the conventional HSP-based methods only "classify" solvents that can and cannot form gels and require many trials to achieve this. For engineering purposes, quantitative estimation of gel properties using the HSP is highly desired.

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Article Synopsis
  • The study investigates how the remnant pancreas regenerates after partial pancreatectomy (PX) and the role of HSP47, a collagen-specific chaperone, in this process.
  • Researchers used siRNA to inhibit HSP47 in activated pancreas stellate cells (aPSCs), aiming to understand its effect on cell proliferation and pancreatic regeneration.
  • Results showed that inhibiting HSP47 suppressed the proliferation of acinar and islet cells, highlighting the significant role of aPSCs and collagen secretion in the regeneration of the remnant pancreas.
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Stellate cells are distributed throughout organs, where, upon chronic damage, they become activated and proliferate to secrete collagen, which results in organ fibrosis. An intriguing property of hepatic stellate cells (HSCs) is that they undergo apoptosis when collagen is resolved by stopping tissue damage or by treatment, even though the mechanisms are unknown. Here we disclose the fact that HSCs, normal diploid cells, acquired dependence on collagen for their growth during the transition from quiescent to active states.

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Purpose: This article describes a method to express implant positions in the dental arch as well as the type and extent of superstructures.

Methods: Basic signs, a 'O' (circle) and a '[symbol: see text]' (dot), which denote an implant and a single standing implant, respectively, are utilized to construct the Panoramic Implant Notation System (PIN System), which allows graphical representation of implants and implant-supported prostheses. The use of the PIN System is described by means of its application to common dental implant situations.

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Background: Periodontal ligament fibroblasts (PDLFs) are the cells essential for periodontal regeneration. PDLFs comprise a heterogeneous cell population and consist of several cell subsets that differ in their function. It is known that PDLFs produce osteoblast-related extracellular matrix proteins and show higher alkaline phosphatase (ALP) activity compared with gingival fibroblasts (GFs), implying that PDLFs have osteogenic characterisitics.

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