Platinum-Catalyzed Diboration of Alkynes by 1,8-Diaminonaphthalene-Protected Diboronic Acid (B(dan)).

The diboration of alkynes by 1,8-diaminonaphthalene-protected diboronic acid (B(dan)) proceeded smoothly in the presence of a platinum catalyst, and 1,2-diborylalkenes were isolated in up to 94% yield. The use of an appropriate solvent and ligand was critical for the progress of the reaction. The derivatization of 1,2-diborylalkenes was briefly examined.

Activation of RAW264.7 macrophages by oxidized galectin-1.

Galectin-1, a member of the beta-galactoside-binding lectin family, exists in both reduced and oxidized states. Oxidized galectin-1 (Gal-1/Ox), which lacks lectin activity, has been shown to promote axonal regeneration after injury by activating macrophages, which causes the release of factors that enhance Schwann cell migration and neurite outgrowth. However, the mechanism of macrophage activation by Gal-1/Ox remains unknown.