Structure and redox behaviour of a paramagnetic Rh-Pt-Cu-Pt-Rh heterometallic-extended metal-atom chain.

A paramagnetic, pentanuclear, metal-metal bonded complex comprising three metals is isolated. The Cu d orbital of the Rh-Pt-Cu-Pt-Rh chain contains an unpaired electron. The close energetic levels and symmetric overlap of the Cu d and Rh-Pt δ* induces a charge-transfer reaction to achieve the diamagnetic Rh-Pt-Cu-Pt-Rh complex.

Geographical distribution and phoretic associations of the viviparous nematode with dung beetles in Japan.

Viviparity is generally considered to be rare in animals. In nematodes, only six species of Rhabditida are viviparous. Five of these species have been identified in association with dung beetles, with being repeatedly isolated from the dung beetle in Japan.

Structural differences between the closely related RNA helicases, UAP56 and URH49, fashion distinct functional apo-complexes.

mRNA export is an essential pathway for the regulation of gene expression. In humans, closely related RNA helicases, UAP56 and URH49, shape selective mRNA export pathways through the formation of distinct complexes, known as apo-TREX and apo-AREX complexes, and their subsequent remodeling into similar ATP-bound complexes. Therefore, defining the unidentified components of the apo-AREX complex and elucidating the molecular mechanisms underlying the formation of distinct apo-complexes is key to understanding their functional divergence.

Photocurrent Induced by a Bicircular Light Drive in Centrosymmetric Systems.

A bicircular light (BCL) consists of left and right circularly polarized lights with different frequencies, and draws a roselike pattern with a rotational symmetry determined by the ratio of the two frequencies. Here we show that an application of a BCL to centrosymmetric systems allows a photocurrent generation through introduction of an effective polarity to the system. We derive formulas for the BCL-induced photocurrent from a standard perturbation theory, which is then applied to a simple 1D model and 3D Dirac and Weyl semimetals.

Onthodiplogaster japonica n. gen., n. sp. (Rhabditida: Diplogastridae) isolated from Onthophagus sp. (Coleoptera: Scarabaeidae) from Japan.

A diplogastrid nematode was isolated from a dung beetle, Onthophagus sp., collected from a rotten mushroom in Kyoto, Japan. The species is characterised by its cheilostomatal shape, separated into 12 narrow plates (rugae), deep stegostom, large ellipsoidal amphids, conical female tail and characteristic receptaculum seminis in the female.

Giant Magnetochiral Anisotropy in Weyl Semimetal WTe_{2} Induced by Diverging Berry Curvature.

The concept of Berry curvature is essential for various transport phenomena. However, an effect of the Berry curvature on magnetochiral anisotropy, i.e.

Asymmetrical Platinum and Rhodium Dinuclear Complex Strongly Bound to Filled d Complexes by Unbridged Pt-Metal Bonds: Toward Heterometallic-Extended Metal Atom Chains.

Heterometallic extended metal atom chains (EMACs) aligned with three types of metal were rationally synthesized by forming unbridged metal-metal bonds based on the interactions between highest occupied and lowest unoccupied molecular orbitals at the d orbital. These chains form pentanuclear structures aligned as Rh-Pt-M-Pt-Rh with relatively large formation constants of 5.0×10  M for M=Pt and 6.

Caspase-Dependent HMGB1 Release from Macrophages Participates in Peripheral Neuropathy Caused by Bortezomib, a Proteasome-Inhibiting Chemotherapeutic Agent, in Mice.

Given the role of macrophage-derived high mobility group box 1 (HMGB1) in chemotherapy-induced peripheral neuropathy (CIPN) caused by paclitaxel, we analyzed the role of HMGB1 and macrophages in the CIPN caused by bortezomib, a proteasome-inhibiting chemotherapeutic agent used for the treatment of multiple myeloma. Repeated administration of bortezomib caused CIPN accompanied by early-stage macrophage accumulation in the dorsal root ganglion. This CIPN was prevented by an anti-HMGB1-neutralizing antibody, thrombomodulin alfa capable of accelerating thrombin-dependent degradation of HMGB1, antagonists of the receptor for advanced glycation end-products (RAGE) and C-X-C motif chemokine receptor 4 (CXCR4), known as HMGB1-targeted membrane receptors, or macrophage depletion with liposomal clodronate, as reported in a CIPN model caused by paclitaxel.

Critical role of Ca3.2 T-type calcium channels in the peripheral neuropathy induced by bortezomib, a proteasome-inhibiting chemotherapeutic agent, in mice.

Bortezomib, a first-line agent for treatment of multiple myeloma, exhibits anticancer activity through proteasome inhibition. However, bortezomib-induced peripheral neuropathy (BIPN) is one of the most serious side effects. Since decreased proteasomal degradation of Ca3.

Strongly Iridescent Hybrid Photonic Sensors Based on Self-Assembled Nanoparticles for Hazardous Solvent Detection.

Facile detection and the identification of hazardous organic solvents are essential for ensuring global safety and avoiding harm to the environment caused by industrial wastes. Here, we present a simple method for the fabrication of silver-coated monodisperse polystyrene nanoparticle photonic structures that are embedded into a polydimethylsiloxane (PDMS) matrix. These hybrid materials exhibit a strong green iridescence with a reflectance peak at 550 nm that originates from the close-packed arrangement of the nanoparticles.